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Atomistry » Magnesium » PDB 3s99-3si8 » 3shz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3s99-3si8 » 3shz » |
Magnesium in PDB 3shz: Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel InhibitorsEnzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
All present enzymatic activity of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors:
3.1.4.35; Protein crystallography data
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shz
was solved by
T.T.Chen,
T.Chen,
Y.C.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3shz:
The structure of Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
(pdb code 3shz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors, PDB code: 3shz: Jump to Magnesium binding site number: 1; 2; 3; 4; 5; Magnesium binding site 1 out of 5 in 3shzGo back to![]() ![]()
Magnesium binding site 1 out
of 5 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
![]() Mono view ![]() Stereo pair view
Magnesium binding site 2 out of 5 in 3shzGo back to![]() ![]()
Magnesium binding site 2 out
of 5 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
![]() Mono view ![]() Stereo pair view
Magnesium binding site 3 out of 5 in 3shzGo back to![]() ![]()
Magnesium binding site 3 out
of 5 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
![]() Mono view ![]() Stereo pair view
Magnesium binding site 4 out of 5 in 3shzGo back to![]() ![]()
Magnesium binding site 4 out
of 5 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
![]() Mono view ![]() Stereo pair view
Magnesium binding site 5 out of 5 in 3shzGo back to![]() ![]()
Magnesium binding site 5 out
of 5 in the Crystal Structure of the PDE5A1 Catalytic Domain in Complex with Novel Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
Z.Xu,
Z.Liu,
T.Chen,
T.T.Chen,
Z.Wang,
G.Tian,
J.Shi,
X.Wang,
Y.Lu,
X.Yan,
G.Wang,
H.Jiang,
K.Chen,
S.Wang,
Y.Xu,
J.Shen,
W.Zhu.
Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem. V. 54 5607 2011.
Page generated: Thu Aug 15 10:59:27 2024
ISSN: ISSN 0022-2623 PubMed: 21714539 DOI: 10.1021/JM200644R |
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