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Magnesium in PDB 4awn: Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate.

Enzymatic activity of Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate.

All present enzymatic activity of Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate.:
3.1.21.1;

Protein crystallography data

The structure of Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate., PDB code: 4awn was solved by G.Parsiegla, C.Noguere, L.Santell, R.A.Lazarus, Y.Bourne, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.13 / 1.95
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 41.960, 58.660, 96.430, 90.00, 90.00, 90.00
R / Rfree (%) 16.6 / 21.9

Other elements in 4awn:

The structure of Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate. also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate. (pdb code 4awn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate., PDB code: 4awn:

Magnesium binding site 1 out of 1 in 4awn

Go back to Magnesium Binding Sites List in 4awn
Magnesium binding site 1 out of 1 in the Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Recombinant Human Dnase I (Rhdnasei) in Complex with Magnesium and Phosphate. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg302

b:24.6
occ:1.00
 O2 A:PO4310 2.0 21.0 1.0
O A:HOH2005 2.0 20.6 1.0
O A:HOH2035 2.1 24.4 1.0
O A:HOH2202 2.1 19.3 1.0
OE2 A:GLU39 2.2 17.0 1.0
O A:HOH2033 2.2 18.5 1.0
P A:PO4310 3.2 24.8 1.0
CD A:GLU39 3.2 18.8 1.0
O3 A:PO4310 3.4 22.7 1.0
OE1 A:GLU39 3.5 17.4 1.0
ND2 A:ASN7 3.8 16.5 1.0
O1 A:PO4310 3.8 22.2 1.0
OD2 A:ASP251 4.0 21.1 1.0
NE2 A:HIS252 4.1 18.7 1.0
OD1 A:ASP251 4.2 19.2 1.0
O4 A:PO4310 4.4 20.8 1.0
O A:HOH2037 4.4 19.0 1.0
OD1 A:ASN7 4.4 16.4 1.0
CG A:ASN7 4.5 16.8 1.0
CD2 A:HIS252 4.5 16.8 1.0
NE2 A:HIS134 4.5 17.9 1.0
CE1 A:HIS134 4.6 18.0 1.0
O A:HOH2205 4.6 30.5 1.0
CG A:ASP251 4.6 18.5 1.0
CG A:GLU39 4.6 17.4 1.0
NE2 A:GLN9 4.7 21.4 1.0
CG A:GLN9 4.7 19.7 1.0
OD2 A:ASP168 4.9 15.7 1.0
O A:HOH2074 4.9 35.4 1.0

Reference:

G.Parsiegla, C.Noguere, L.Santell, R.A.Lazarus, Y.Bourne. The Structure of Human Dnase I Bound to Magnesium and Phosphate Ions Points to A Catalytic Mechanism Common to Members of the Dnase I-Like Superfamily. Biochemistry V. 51 10250 2012.
ISSN: ISSN 0006-2960
PubMed: 23215638
DOI: 10.1021/BI300873F
Page generated: Mon Aug 11 06:05:10 2025

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