Magnesium in PDB 4cls: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate

Enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate

All present enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate:
4.6.1.1;

Protein crystallography data

The structure of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate, PDB code: 4cls was solved by S.Kleinboelting, M.Weyand, C.Steegborn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	86.68 / 1.85
*Space group*	P 6₃
*Cell size a, b, c (Å), α, β, γ (°)*	100.090, 100.090, 97.750, 90.00, 90.00, 120.00
*R / R_free (%)*	17.36 / 21.38

Other elements in 4cls:

The structure of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate (pdb code 4cls). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate, PDB code: 4cls:

Magnesium binding site 1 out of 1 in 4cls

Go back to

Magnesium Binding Sites List in 4cls

Magnesium binding site 1 out of 1 in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mg1468 b:55.3 occ:1.00	OD1	A:ASP99	2.2	51.0	1.0
	OD1	A:ASP47	2.6	45.9	1.0
	O3	A:POP1470	2.9	66.7	1.0
	O	A:POP1470	3.1	84.5	1.0
	O4	A:POP1470	3.2	80.7	1.0
	CG	A:ASP99	3.3	50.1	1.0
	CG	A:ASP47	3.6	47.9	1.0
	OD2	A:ASP99	3.7	56.0	1.0
	P2	A:POP1470	3.7	85.2	1.0
	P1	A:POP1470	3.7	75.2	1.0
	O	A:ILE48	3.9	62.3	1.0
	OD2	A:ASP47	3.9	40.0	1.0
	O6	A:POP1470	4.0	94.0	1.0
	O1	A:POP1470	4.3	73.7	1.0
	CB	A:ALA100	4.5	28.9	1.0
	N	A:ASP99	4.5	40.5	1.0
	CB	A:ASP99	4.5	46.8	1.0
	C	A:ASP99	4.6	34.0	1.0
	N	A:ALA100	4.6	33.7	1.0
	CA	A:ASP99	4.8	42.9	1.0
	C	A:ILE48	4.8	52.7	1.0
	CB	A:ASP47	4.9	39.3	1.0
	O2	A:POP1470	5.0	72.5	1.0
	O	A:ASP99	5.0	35.3	1.0

Reference:

S.Kleinboelting, A.Diaz, S.Moniot, J.Van Den Heuvel, M.Weyand, L.R.Levin, J.Buck, C.Steegborn. Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of Its Activation Through Bicarbonate. Proc.Natl.Acad.Sci.Usa V. 111 3727 2014.
ISSN: ISSN 0027-8424
PubMed: 24567411
DOI: 10.1073/PNAS.1322778111

Page generated: Mon Aug 11 07:16:09 2025

Last articles

Mg in 5QIN
Mg in 5PRC
Mg in 5PNV
Mg in 5PNW
Mg in 5PNU
Mg in 5PNS
Mg in 5PNR
Mg in 5PNQ
Mg in 5PNP
Mg in 5PNO

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy