Magnesium in PDB 4lx0: Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A

The structure of Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A, PDB code: 4lx0 was solved by O.Pylypenko, W.Attanda, C.Gauquelin, A.Houdusse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.50 / 2.19
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	95.100, 125.920, 157.660, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 21.8

The structure of Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A also contains other interesting chemical elements:

Fluorine

(F)

6 atoms

The binding sites of Magnesium atom in the Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A (pdb code 4lx0). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A, PDB code: 4lx0:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg201 b:43.0 occ:1.00 O1B A:GDP203 2.0 38.5 1.0 OG A:SER25 2.0 46.7 1.0 OG1 A:THR43 2.1 47.9 1.0 O A:HOH303 2.1 38.3 1.0 O A:HOH311 2.1 42.1 1.0 F3 A:BEF202 2.2 45.6 1.0 CB A:SER25 3.0 40.5 1.0 CB A:THR43 3.1 49.8 1.0 PB A:GDP203 3.2 43.0 1.0 BE A:BEF202 3.3 44.1 1.0 O3B A:GDP203 3.5 40.4 1.0 N A:SER25 3.7 39.0 1.0 N A:THR43 3.8 45.7 1.0 OD2 A:ASP66 3.9 44.4 1.0 CA A:SER25 3.9 41.8 1.0 OD1 A:ASP66 4.0 41.0 1.0 F1 A:BEF202 4.0 42.4 1.0 CA A:THR43 4.1 43.8 1.0 CG2 A:THR43 4.2 39.8 1.0 O2B A:GDP203 4.2 39.5 1.0 O A:HOH304 4.2 49.4 1.0 O2A A:GDP203 4.3 44.6 1.0 CG A:ASP66 4.3 46.0 1.0 O3A A:GDP203 4.4 43.6 1.0 F2 A:BEF202 4.4 43.6 1.0 O A:THR67 4.6 36.0 1.0 PA A:GDP203 4.6 43.8 1.0 O A:LYS41 4.7 50.1 1.0 O1A A:GDP203 4.7 45.0 1.0 CB A:LYS24 4.7 38.0 1.0 C A:LYS24 4.8 40.7 1.0 C A:SER42 4.8 45.0 1.0 CE A:LYS24 4.9 47.5 1.0 NZ A:LYS24 5.0 46.2 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of MYO5B Globular Tail Domain in Complex with Active RAB11A within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg201 b:58.2 occ:1.00 OG C:SER25 2.1 55.5 1.0 O C:HOH339 2.1 56.5 1.0 O C:HOH336 2.1 52.0 1.0 OG1 C:THR43 2.1 58.7 1.0 O1B C:GDP203 2.2 50.8 1.0 F3 C:BEF202 2.2 54.7 1.0 CB C:THR43 3.0 57.9 1.0 CB C:SER25 3.1 56.0 1.0 BE C:BEF202 3.3 50.9 1.0 PB C:GDP203 3.4 52.4 1.0 N C:THR43 3.6 64.8 1.0 O3B C:GDP203 3.7 61.2 1.0 OD2 C:ASP66 3.9 63.8 1.0 N C:SER25 3.9 60.9 1.0 CA C:THR43 3.9 53.0 1.0 F1 C:BEF202 4.0 49.3 1.0 CA C:SER25 4.1 57.5 1.0 OD1 C:ASP66 4.1 63.4 1.0 CG2 C:THR43 4.1 53.1 1.0 O2A C:GDP203 4.2 65.2 1.0 O C:HOH303 4.2 68.8 1.0 CG C:ASP66 4.4 63.6 1.0 O2B C:GDP203 4.4 47.3 1.0 F2 C:BEF202 4.4 52.3 1.0 O C:LYS41 4.5 68.7 1.0 O3A C:GDP203 4.5 51.3 1.0 O C:THR67 4.6 62.9 1.0 C C:SER42 4.7 66.3 1.0 PA C:GDP203 4.7 55.1 1.0 O1A C:GDP203 4.8 55.7 1.0 O C:HOH319 4.9 82.7 1.0 CB C:LYS24 5.0 55.7 1.0 C C:LYS24 5.0 61.1 1.0 CA C:SER42 5.0 64.8 1.0

O.Pylypenko, W.Attanda, C.Gauquelin, M.Lahmani, D.Coulibaly, B.Baron, S.Hoos, M.A.Titus, P.England, A.M.Houdusse. Structural Basis of Myosin V Rab Gtpase-Dependent Cargo Recognition. Proc.Natl.Acad.Sci.Usa V. 110 20443 2013.
ISSN: ISSN 0027-8424
PubMed: 24248336
DOI: 10.1073/PNAS.1314329110