Magnesium in PDB 4mg2: ALKBH2 F102A Cross-Linked to Undamaged Dsdna

All present enzymatic activity of ALKBH2 F102A Cross-Linked to Undamaged Dsdna:
1.14.11.33;

The structure of ALKBH2 F102A Cross-Linked to Undamaged Dsdna, PDB code: 4mg2 was solved by B.Chen, J.Gan, C.G.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.30
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	129.997, 129.997, 84.825, 90.00, 90.00, 120.00
R / Rfree (%)	23.4 / 27.9

The binding sites of Magnesium atom in the ALKBH2 F102A Cross-Linked to Undamaged Dsdna (pdb code 4mg2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the ALKBH2 F102A Cross-Linked to Undamaged Dsdna, PDB code: 4mg2:

Magnesium binding site 1 out of 1 in the ALKBH2 F102A Cross-Linked to Undamaged Dsdna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of ALKBH2 F102A Cross-Linked to Undamaged Dsdna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:34.8 occ:1.00 O A:HOH422 2.0 48.4 1.0 CE1 A:HIS171 2.1 62.0 1.0 OD1 A:ASP173 2.2 54.2 1.0 NE2 A:HIS171 2.2 62.4 1.0 NE2 A:HIS236 2.2 49.4 1.0 O A:HOH424 2.2 48.6 1.0 O A:HOH423 2.4 50.6 1.0 CD2 A:HIS236 3.2 51.9 1.0 CG A:ASP173 3.2 60.5 1.0 CE1 A:HIS236 3.2 50.4 1.0 ND1 A:HIS171 3.4 67.7 1.0 CD2 A:HIS171 3.5 66.3 1.0 OD2 A:ASP173 3.5 57.6 1.0 CG A:HIS171 4.1 68.2 1.0 ND1 A:HIS236 4.3 52.4 1.0 CG A:HIS236 4.3 53.3 1.0 CB A:ASP173 4.6 60.1 1.0 N A:ASP173 4.7 61.6 1.0 CA A:ASP173 4.8 62.8 1.0 CD1 A:ILE168 4.9 50.7 1.0

B.Chen, J.Gan, C.G.Yang. The Complex Structures of ALKBH2 Mutants Cross-Linked to Dsdna Reveal the Conformational Swing of β-Hairpin Sci China Chem V. 57 307 2014.
ISSN: ISSN 1674-7291
DOI: 10.1007/S11426-013-5029-Z