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Atomistry » Magnesium » PDB 4nm0-4nxn » 4npv » |
Magnesium in PDB 4npv: Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine)Enzymatic activity of Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine)
All present enzymatic activity of Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine):
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine), PDB code: 4npv
was solved by
J.Pandit,
A.Evdomikov,
M.Mansour,
S.Simons,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4npv:
The structure of Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine) also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine)
(pdb code 4npv). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine), PDB code: 4npv: Magnesium binding site 1 out of 1 in 4npvGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human PDE1B Bound to Inhibitor 7A (6,7,8- Trimethoxy-N-(Pentan-3-Yl)Quinazolin-4-Amine)
![]() Mono view ![]() Stereo pair view
Reference:
J.M.Humphrey,
E.X.Yang,
C.W.Am Ende,
E.P.Arnold,
J.L.Head,
S.Jenkinsonb,
L.A.Lebel,
S.Liras,
J.Pandit,
B.Samas,
F.Vajdos,
S.P.Simons,
A.Evdokimova,
M.Mansour,
F.S.Menniti.
Small-Molecule Phosphodiesterase Probes: Discovery of Potent and Selective Cns-Penetrable Quinazoline Inhibitors of PDE1 Medchemcomm 2014.
Page generated: Mon Aug 19 23:43:31 2024
ISSN: ESSN 2040-2511 DOI: 10.1039/C4MD00113C |
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