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Atomistry » Magnesium » PDB 4o5w-4ogu » 4od0 » |
Magnesium in PDB 4od0: Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]UreaEnzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea
All present enzymatic activity of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea:
3.1.3.76; 3.3.2.10; Protein crystallography data
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea, PDB code: 4od0
was solved by
K.S.S.Lee,
J.Liu,
K.M.Wagner,
S.Pakhomova,
H.Dong,
C.Morisseau,
S.H.Fu,
J.Yang,
P.Wang,
A.Ulu,
C.Mate,
L.Nguyen,
H.Wullf,
M.L.Eldin,
A.A.Mara,
M.E.Newcomer,
D.C.Zeldin,
B.D.Hammock,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4od0:
The structure of Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea
(pdb code 4od0). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea, PDB code: 4od0: Magnesium binding site 1 out of 1 in 4od0Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human Soluble Epoxide Hydrolase Complexed with 1- (1-Propanoylpiperidin-4-Yl)-3-[4-(Trifluoromethoxy)Phenyl]Urea
![]() Mono view ![]() Stereo pair view
Reference:
K.S.Lee,
J.Y.Liu,
K.M.Wagner,
S.Pakhomova,
H.Dong,
C.Morisseau,
S.H.Fu,
J.Yang,
P.Wang,
A.Ulu,
C.A.Mate,
L.V.Nguyen,
S.H.Hwang,
M.L.Edin,
A.A.Mara,
H.Wulff,
M.E.Newcomer,
D.C.Zeldin,
B.D.Hammock.
Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy. J.Med.Chem. V. 57 7016 2014.
Page generated: Tue Aug 20 00:47:11 2024
ISSN: ISSN 0022-2623 PubMed: 25079952 DOI: 10.1021/JM500694P |
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