Magnesium in PDB 4ofz: Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi

All present enzymatic activity of Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi:
3.1.3.12;

The structure of Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi, PDB code: 4ofz was solved by J.D.Farelli, K.N.Allen, C.K.S Carlow, D.Dunaway-Mariano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.91 / 3.00
Space group	P 64 2 2
Cell size a, b, c (Å), α, β, γ (°)	166.940, 166.940, 99.562, 90.00, 90.00, 120.00
R / Rfree (%)	21.6 / 27.3

The binding sites of Magnesium atom in the Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi (pdb code 4ofz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi, PDB code: 4ofz:

Magnesium binding site 1 out of 1 in the Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Unliganded Trehalose-6-Phosphate Phosphatase From Brugia Malayi within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:41.4 occ:1.00 O A:HOH653 2.3 51.4 1.0 OD1 A:ASP424 2.4 55.9 1.0 O A:ASP215 2.6 63.6 1.0 OD1 A:ASP213 2.8 43.9 1.0 CG A:ASP424 3.2 50.9 1.0 OD2 A:ASP424 3.3 43.3 1.0 OH A:TYR221 3.3 45.7 1.0 CG A:ASP213 3.6 34.5 1.0 OD2 A:ASP213 3.6 46.1 1.0 CG2 A:THR425 3.7 17.7 1.0 C A:ASP215 3.7 59.8 1.0 CB A:ASP215 4.1 65.8 1.0 CA A:ASP215 4.3 54.5 1.0 CZ A:TYR221 4.3 58.2 1.0 OG1 A:THR425 4.4 46.4 1.0 N A:ASP215 4.4 48.0 1.0 CE1 A:TYR221 4.5 54.7 1.0 CB A:THR425 4.7 26.2 1.0 CB A:ASP424 4.7 33.8 1.0 N A:THR425 4.7 47.7 1.0 OD2 A:ASP428 4.8 55.8 1.0 N A:GLY216 4.8 37.4 1.0 NZ A:LYS398 4.9 47.3 1.0 OG1 A:THR217 4.9 43.4 1.0 CB A:ASP213 4.9 27.7 1.0

J.D.Farelli, B.D.Galvin, Z.Li, C.Liu, M.Aono, M.Garland, O.E.Hallett, T.B.Causey, A.Ali-Reynolds, D.J.Saltzberg, C.K.Carlow, D.Dunaway-Mariano, K.N.Allen. Structure of the Trehalose-6-Phosphate Phosphatase From Brugia Malayi Reveals Key Design Principles For Anthelmintic Drugs. Plos Pathog. V. 10 04245 2014.
ISSN: ISSN 1553-7366
PubMed: 24992307
DOI: 10.1371/JOURNAL.PPAT.1004245