Atomistry » Magnesium » PDB 4pyl-4q8b » 4pzz
Atomistry »
  Magnesium »
    PDB 4pyl-4q8b »
      4pzz »

Magnesium in PDB 4pzz: Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands

Enzymatic activity of Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands

All present enzymatic activity of Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands:
3.6.5.2;

Protein crystallography data

The structure of Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands, PDB code: 4pzz was solved by Q.Sun, J.Phan, A.Friberg, D.V.Camper, E.T.Olejniczak, S.W.Fesik, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.31 / 1.40
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 39.076, 41.063, 91.678, 90.00, 90.00, 90.00
R / Rfree (%) 13.1 / 15.6

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands (pdb code 4pzz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands, PDB code: 4pzz:

Magnesium binding site 1 out of 1 in 4pzz

Go back to Magnesium Binding Sites List in 4pzz
Magnesium binding site 1 out of 1 in the Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Second-Site Screening of K-Ras in the Presence of Covalently Attached First-Site Ligands within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg202

b:8.8
occ:1.00
 O3B A:GDP201 2.0 8.0 1.0
O A:HOH309 2.1 8.7 1.0
O A:HOH305 2.1 9.6 1.0
O A:HOH302 2.1 8.2 1.0
O A:HOH304 2.1 9.5 1.0
OG A:SER17 2.2 7.4 1.0
HB2 A:SER17 3.2 10.0 1.0
CB A:SER17 3.2 8.3 1.0
PB A:GDP201 3.3 8.3 1.0
H A:SER17 3.3 8.8 1.0
O1B A:GDP201 3.5 9.1 1.0
HA A:PRO34 3.5 14.1 1.0
HD2 A:TYR32 3.5 16.2 1.0
HB3 A:SER17 3.9 10.0 1.0
N A:SER17 3.9 7.4 1.0
HB2 A:LYS16 4.0 8.4 1.0
HE2 A:LYS16 4.0 10.7 1.0
CA A:SER17 4.1 6.5 1.0
O1A A:GDP201 4.2 10.7 1.0
OD2 A:ASP57 4.2 9.8 1.0
O A:PRO34 4.3 11.2 1.0
O A:ASP33 4.3 11.7 1.0
OD1 A:ASP57 4.3 8.2 1.0
O3A A:GDP201 4.3 8.8 1.0
O2B A:GDP201 4.3 8.9 1.0
HE2 A:TYR32 4.4 25.0 1.0
CD2 A:TYR32 4.4 13.5 1.0
CA A:PRO34 4.4 11.8 1.0
O A:ILE36 4.4 10.8 1.0
HA A:SER17 4.4 7.8 1.0
PA A:GDP201 4.6 9.4 1.0
O A:THR58 4.6 9.3 1.0
HB2 A:ALA59 4.6 15.4 1.0
C A:PRO34 4.6 11.0 1.0
CG A:ASP57 4.6 8.3 1.0
HZ3 A:LYS16 4.6 12.6 1.0
O2A A:GDP201 4.7 10.8 1.0
CE2 A:TYR32 4.8 20.8 1.0
HA A:ALA59 4.9 13.1 1.0
HZ2 A:LYS16 4.9 12.6 1.0
CE A:LYS16 4.9 8.9 1.0
O A:HOH321 4.9 10.7 1.0
CB A:LYS16 4.9 7.0 1.0
HB3 A:TYR32 4.9 17.8 1.0
O A:TYR32 4.9 13.4 1.0

Reference:

Q.Sun, J.Phan, A.R.Friberg, D.V.Camper, E.T.Olejniczak, S.W.Fesik. A Method For the Second-Site Screening of K-Ras in the Presence of A Covalently Attached First-Site Ligand. J.Biomol.uc(Nmr) V. 60 11 2014.
ISSN: ISSN 0925-2738
PubMed: 25087006
DOI: 10.1007/S10858-014-9849-8
Page generated: Tue Aug 20 01:42:59 2024

Last articles

Cl in 8UR4
Cl in 8UR1
Cl in 8UQY
Cl in 8UQZ
Cl in 8UQX
Cl in 8UQW
Cl in 8UQB
Cl in 8UP3
Cl in 8UQA
Cl in 8UPN
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy