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Atomistry » Magnesium » PDB 5dt3-5e79 » 5dt4 » |
Magnesium in PDB 5dt4: Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122Enzymatic activity of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
All present enzymatic activity of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122:
2.7.11.1; Protein crystallography data
The structure of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122, PDB code: 5dt4
was solved by
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
G.J.Mckenzie,
D.J.Huggins,
S.Stockwell,
J.A.Stokes,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
A.R.Venkitaraman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5dt4:
The structure of Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
(pdb code 5dt4). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122, PDB code: 5dt4: Magnesium binding site 1 out of 1 in 5dt4Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Aurora A Kinase in Complex with AA35 and Atp in Space Group P6122
![]() Mono view ![]() Stereo pair view
Reference:
M.Janecek,
M.Rossmann,
P.Sharma,
A.Emery,
D.J.Huggins,
S.R.Stockwell,
J.E.Stokes,
Y.S.Tan,
E.G.Almeida,
B.Hardwick,
A.J.Narvaez,
M.Hyvonen,
D.R.Spring,
G.J.Mckenzie,
A.R.Venkitaraman.
Allosteric Modulation of Aurka Kinase Activity By A Small-Molecule Inhibitor of Its Protein-Protein Interaction with TPX2. Sci Rep V. 6 28528 2016.
Page generated: Tue Aug 12 07:27:33 2025
ISSN: ESSN 2045-2322 PubMed: 27339427 DOI: 10.1038/SREP28528 |
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