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Atomistry » Magnesium » PDB 5h2q-5hia » 5he3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 5h2q-5hia » 5he3 » |
Magnesium in PDB 5he3: Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411Enzymatic activity of Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411
All present enzymatic activity of Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411:
2.7.11.15; Protein crystallography data
The structure of Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411, PDB code: 5he3
was solved by
M.C.Cato,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5he3:
The structure of Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411
(pdb code 5he3). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411, PDB code: 5he3: Magnesium binding site 1 out of 1 in 5he3Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Bovine GRK2 in Complex with Gbetagamma Subunits and CCG224411
![]() Mono view ![]() Stereo pair view
Reference:
H.V.Waldschmidt,
K.T.Homan,
O.Cruz-Rodriguez,
M.C.Cato,
J.Waninger-Saroni,
K.M.Larimore,
A.Cannavo,
J.Song,
J.Y.Cheung,
P.D.Kirchhoff,
W.J.Koch,
J.J.Tesmer,
S.D.Larsen.
Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J.Med.Chem. V. 59 3793 2016.
Page generated: Sun Sep 29 15:48:10 2024
ISSN: ISSN 0022-2623 PubMed: 27050625 DOI: 10.1021/ACS.JMEDCHEM.5B02000 |
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