|
Atomistry » Magnesium » PDB 5ses-5sfv » 5sf2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 5ses-5sfv » 5sf2 » |
Magnesium in PDB 5sf2: Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-CarboxamideEnzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide, PDB code: 5sf2
was solved by
C.Joseph,
K.Groebke-Zbinden,
J.Benz,
D.Schlatter,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5sf2:
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide
(pdb code 5sf2). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide, PDB code: 5sf2: Magnesium binding site 1 out of 1 in 5sf2Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Cyclopropyl-N-(3-Oxo-1,2-Dihydroisoindol-5-Yl)-3-(Pyrimidin-5- Ylamino)Pyridine-2-Carboxamide
![]() Mono view ![]() Stereo pair view
Reference:
A.Tosstorff,
M.G.Rudolph,
J.C.Cole,
M.Reutlinger,
C.Kramer,
H.Schaffhauser,
A.Nilly,
A.Flohr,
B.Kuhn.
A High Quality, Industrial Data Set For Binding Affinity Prediction: Performance Comparison in Different Early Drug Discovery Scenarios. J.Comput.Aided Mol.Des. V. 36 753 2022.
Page generated: Mon Sep 30 03:30:09 2024
ISSN: ESSN 1573-4951 PubMed: 36153472 DOI: 10.1007/S10822-022-00478-X |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |