Magnesium in PDB 6ao5: Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain

All present enzymatic activity of Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain:
2.7.11.1;

The structure of Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain, PDB code: 6ao5 was solved by D.R.Tomchick, X.Luo, L.Ni, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.27 / 2.96
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	223.678, 223.678, 79.645, 90.00, 90.00, 120.00
R / Rfree (%)	23.5 / 25.6

The binding sites of Magnesium atom in the Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain (pdb code 6ao5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain, PDB code: 6ao5:

Magnesium binding site 1 out of 1 in the Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human MST2 in Complex with SAV1 Sarah Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:30.6 occ:1.00 O1B A:ANP501 2.2 37.7 1.0 OD2 A:ASP164 2.2 45.8 1.0 OD1 A:ASN151 2.3 23.3 1.0 O1G A:ANP501 2.6 34.9 1.0 O1A A:ANP501 2.7 48.1 1.0 HA A:ASN151 3.3 28.3 1.0 CG A:ASP164 3.4 45.8 1.0 CG A:ASN151 3.5 22.8 1.0 O5' A:ANP501 3.5 34.0 1.0 PB A:ANP501 3.6 36.7 1.0 PA A:ANP501 3.6 47.9 1.0 O A:GLY150 3.7 23.2 1.0 HZ3 A:LYS56 3.7 79.3 1.0 H8 A:ANP501 3.8 33.6 1.0 PG A:ANP501 4.0 34.5 1.0 CA A:ASN151 4.1 23.2 1.0 HB2 A:ASP164 4.1 54.4 1.0 H3' A:ANP501 4.1 43.7 1.0 OD1 A:ASP164 4.2 46.5 1.0 O3A A:ANP501 4.2 0.5 1.0 CB A:ASN151 4.3 22.9 1.0 C A:GLY150 4.3 22.5 1.0 HD21 A:LEU153 4.3 30.1 1.0 CB A:ASP164 4.4 44.9 1.0 N3B A:ANP501 4.4 85.2 1.0 N A:ASN151 4.4 22.7 1.0 ND2 A:ASN151 4.5 22.3 1.0 HB3 A:ALA163 4.5 27.7 1.0 HD21 A:ASN151 4.5 27.2 1.0 HB3 A:ASN151 4.5 27.9 1.0 C8 A:ANP501 4.5 27.6 1.0 HZ1 A:LYS56 4.5 79.3 1.0 NZ A:LYS56 4.5 65.7 1.0 O2G A:ANP501 4.5 0.5 1.0 O2B A:ANP501 4.6 35.1 1.0 HNB1 A:ANP501 4.6 0.8 1.0 HB3 A:ASP164 4.8 54.4 1.0 C5' A:ANP501 4.8 34.2 1.0 HD11 A:LEU153 4.8 31.6 1.0 HB1 A:ALA163 4.9 27.7 1.0 HZ2 A:LYS56 4.9 79.3 1.0 C3' A:ANP501 5.0 36.0 1.0

S.J.Bae, L.Ni, A.Osinski, D.R.Tomchick, C.A.Brautigam, X.Luo. SAV1 Promotes Hippo Kinase Activation Through Antagonizing the PP2A Phosphatase Stripak. Elife V. 6 2017.
ISSN: ESSN 2050-084X
PubMed: 29063833
DOI: 10.7554/ELIFE.30278