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Atomistry » Magnesium » PDB 6f6u-6fch » 6f7b » |
Magnesium in PDB 6f7b: Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032Enzymatic activity of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
All present enzymatic activity of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032, PDB code: 6f7b
was solved by
S.J.Holton,
G.Siemeister,
A.Mengel,
W.Bone,
J.Schroeder,
S.Zitzmann-Kolbe,
H.Briem,
A.Fernandez-Montalvan,
S.Prechtl,
U.Moenning,
O.Von Ahsen,
J.Johanssen,
A.Cleve,
V.Puetter,
M.Hitchcock,
F.Von Nussbaum,
M.Brands,
D.Mumberg,
K.Ziegelbauer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6f7b:
The structure of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
(pdb code 6f7b). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032, PDB code: 6f7b: Magnesium binding site 1 out of 1 in 6f7bGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
![]() Mono view ![]() Stereo pair view
Reference:
G.Siemeister,
A.Mengel,
A.E.Fernandez-Montalvan,
W.Bone,
J.Schroder,
S.Zitzmann-Kolbe,
H.Briem,
S.Prechtl,
S.J.Holton,
U.Monning,
O.Von Ahsen,
S.Johanssen,
A.Cleve,
V.Putter,
M.Hitchcock,
F.Von Nussbaum,
M.Brands,
K.Ziegelbauer,
D.Mumberg.
Inhibition of BUB1 Kinase By Bay 1816032 Sensitizes Tumor Cells Toward Taxanes, Atr, and Parp Inhibitorsin Vitroandin Vivo. Clin.Cancer Res. V. 25 1404 2019.
Page generated: Tue Oct 1 00:10:53 2024
ISSN: ISSN 1078-0432 PubMed: 30429199 DOI: 10.1158/1078-0432.CCR-18-0628 |
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