Magnesium in PDB 6gxx: Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation

The structure of Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation, PDB code: 6gxx was solved by E.L.K.Elliston, E.Miranda, J.Perez, D.A.Lomas, J.A.Irving, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.08 / 1.85
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	54.103, 85.257, 89.427, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 22.3

The binding sites of Magnesium atom in the Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation (pdb code 6gxx). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation, PDB code: 6gxx:

Magnesium binding site 1 out of 1 in the Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Fab Fragment of An Antibody Selective For Alpha-1-Antitrypsin in the Native Conformation within 5.0Å range: probe atom residue distance (Å) B Occ L:Mg301 b:31.6 occ:1.00 OH L:TYR173 2.7 24.9 1.0 O L:HOH549 2.9 17.4 1.0 OH L:TYR140 2.9 21.7 1.0 CE2 L:TYR140 3.2 16.5 1.0 O L:HOH632 3.4 34.1 1.0 CZ L:TYR140 3.4 11.8 1.0 CE1 L:TYR173 3.6 21.2 1.0 CZ L:TYR173 3.6 19.4 1.0 CB L:GLU105 3.7 18.1 1.0 CB L:ALA12 3.7 16.2 1.0 O L:ILE106 3.9 11.0 1.0 O L:HOH616 4.0 35.0 1.0 NE2 L:GLN166 4.2 9.6 1.0 CD2 L:TYR140 4.4 10.5 1.0 O L:HOH680 4.5 26.4 1.0 O L:HOH403 4.6 35.5 1.0 CA L:ALA12 4.7 10.5 1.0 CE1 L:TYR140 4.7 14.0 1.0 C L:ILE106 4.7 11.6 1.0 O L:HOH650 4.8 32.2 1.0 CD L:GLN166 4.8 14.3 1.0 CD1 L:TYR173 4.9 12.6 1.0 CE2 L:TYR173 4.9 16.4 1.0 O L:HOH603 4.9 19.6 1.0 CA L:GLU105 4.9 8.6 1.0 N L:ILE106 5.0 9.0 1.0 C L:GLU105 5.0 11.9 1.0

E.L.K.Elliston, E.Miranda, J.Perez, J.A.Irving, D.A.Lomas. Characterisation of A Monoclonal Antibody Conformationally-Selective For Native Alpha-1-Antitrypsin To Be Published.