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Magnesium in PDB 6koq: Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt

Enzymatic activity of Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt

All present enzymatic activity of Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt:
2.7.7.6;

Protein crystallography data

The structure of Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt, PDB code: 6koq was solved by L.Li, Y.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.51 / 3.35
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 126.846, 161.097, 129.551, 90.00, 117.44, 90.00
R / Rfree (%) 22.1 / 26

Other elements in 6koq:

The structure of Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt (pdb code 6koq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt, PDB code: 6koq:

Magnesium binding site 1 out of 1 in 6koq

Go back to Magnesium Binding Sites List in 6koq
Magnesium binding site 1 out of 1 in the Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mycobacterium Tuberculosis Initial Transcription Complex Comprising Sigma H and 5'-Oh Rna of 10 Nt within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg2003

b:68.6
occ:1.00
OD1 D:ASP535 1.8 69.7 1.0
OD1 D:ASP537 2.1 65.5 1.0
OD1 D:ASP539 2.2 66.9 1.0
OD2 D:ASP535 2.3 74.1 1.0
O3' I:A10 2.3 70.9 1.0
CG D:ASP535 2.4 70.9 1.0
CG D:ASP537 2.8 64.8 1.0
OD2 D:ASP537 2.9 64.6 1.0
CG D:ASP539 3.0 65.9 1.0
O2' I:A10 3.0 59.1 1.0
OD2 D:ASP539 3.1 69.2 1.0
C3' I:A10 3.4 60.9 1.0
C2' I:A10 3.7 57.8 1.0
CB D:ASP535 3.9 55.7 1.0
C4' I:A10 4.0 62.3 1.0
CB D:ASP537 4.2 61.0 1.0
CB D:ASP539 4.4 62.0 1.0
N D:ASP537 4.4 63.6 1.0
N D:ASP535 4.5 69.0 1.0
CA D:ASP535 4.5 61.9 1.0
C D:ASP535 4.6 67.0 1.0
NH2 D:ARG500 4.6 65.8 1.0
O D:ASP535 4.7 69.8 1.0
CA D:ASP537 4.7 59.7 1.0
N D:ASP539 4.8 69.0 1.0
C D:ASP537 4.9 64.4 1.0
O D:HOH2102 4.9 61.5 1.0
CA D:ASP539 4.9 59.6 1.0
C1' I:A10 5.0 62.0 1.0
C5' I:A10 5.0 56.9 1.0

Reference:

L.Li, V.Molodtsov, W.Lin, R.H.Ebright, Y.Zhang. Rna Extension Drives A Stepwise Displacement of An Initiation-Factor Structural Module in Initial Transcription Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
DOI: 10.1073/PNAS.1920747117
Page generated: Tue Oct 1 07:19:32 2024

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