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Atomistry » Magnesium » PDB 6m69-6mlw » 6mep » |
Magnesium in PDB 6mep: Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437Enzymatic activity of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437
All present enzymatic activity of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437, PDB code: 6mep
was solved by
C.Da,
D.Zhang,
M.A.Stashko,
A.Cheng,
D.Hunter,
J.Norris-Drouin,
L.Graves,
M.Machius,
M.J.Miley,
D.Deryckere,
H.S.Earp,
D.K.Graham,
S.V.Frye,
X.Wang,
D.Kireev,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6mep:
The structure of Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437
(pdb code 6mep). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437, PDB code: 6mep: Magnesium binding site 1 out of 1 in 6mepGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of the Catalytic Domain of the Proto-Oncogene Tyrosine-Protein Kinase Mer in Complex with Inhibitor UNC3437
![]() Mono view ![]() Stereo pair view
Reference:
C.Da,
D.Zhang,
M.Stashko,
E.Vasileiadi,
R.E.Parker,
K.A.Minson,
M.G.Huey,
J.M.Huelse,
D.Hunter,
T.S.K.Gilbert,
J.Norris-Drouin,
M.Miley,
L.E.Herring,
L.M.Graves,
D.Deryckere,
H.S.Earp,
D.K.Graham,
S.V.Frye,
X.Wang,
D.Kireev.
Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology. J.Am.Chem.Soc. V. 141 15700 2019.
Page generated: Tue Oct 1 11:36:31 2024
ISSN: ESSN 1520-5126 PubMed: 31497954 DOI: 10.1021/JACS.9B08660 |
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