Magnesium in PDB 6mn8: Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide

The structure of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide, PDB code: 6mn8 was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.28 / 2.35
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	159.720, 159.720, 143.720, 90.00, 90.00, 120.00
R / Rfree (%)	14.2 / 18

The structure of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide also contains other interesting chemical elements:

Bromine	(Br)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Magnesium atom in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide (pdb code 6mn8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide, PDB code: 6mn8:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:46.8 occ:1.00 O A:VAL172 2.2 32.7 1.0 O A:SER293 2.3 30.9 1.0 O A:HOH782 2.4 30.0 1.0 O A:HOH737 2.5 50.4 1.0 O A:HOH747 2.6 49.5 1.0 O A:HOH839 2.9 61.9 1.0 C A:VAL172 3.4 32.2 1.0 C A:SER293 3.5 32.0 1.0 CA A:GLN173 3.9 37.3 1.0 N A:SER293 4.0 29.5 1.0 O A:ALA169 4.1 35.5 1.0 OG A:SER293 4.1 38.3 1.0 N A:GLN173 4.1 36.0 1.0 CA A:SER293 4.3 31.5 1.0 O A:GLN173 4.4 41.5 1.0 C A:GLN173 4.4 38.8 1.0 N A:PHE294 4.5 32.9 1.0 CA A:VAL172 4.5 30.3 1.0 CG1 A:VAL172 4.6 25.7 1.0 CB A:VAL172 4.6 33.3 1.0 CA A:PHE294 4.7 31.2 1.0 O A:HOH815 4.8 49.4 1.0 CB A:SER293 4.8 33.1 1.0 O A:ASN291 4.9 28.8 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:34.5 occ:1.00 O A:HOH725 1.9 30.8 1.0 O A:HOH731 1.9 40.9 1.0 O2B A:ANP604 2.0 27.0 0.5 O3G A:ANP604 2.1 39.1 0.5 O2 A:2PN606 2.1 39.1 0.5 O A:HOH768 2.1 33.1 1.0 O A:HOH750 2.1 33.9 1.0 O A:HOH703 2.2 25.7 0.5 PG A:ANP604 3.2 41.9 0.5 P1 A:2PN606 3.3 41.6 0.5 PB A:ANP604 3.3 22.0 0.5 O1 A:2PN606 3.4 36.6 0.5 N3B A:ANP604 3.6 33.9 0.5 NH1 A:ARG190 3.7 25.2 1.0 O A:HOH702 3.8 27.7 0.5 O1G A:ANP604 3.9 52.1 0.5 N1 A:2PN606 4.1 50.8 0.5 NH1 A:ARG201 4.1 32.0 1.0 OE2 A:GLU192 4.1 40.0 1.0 O1B A:ANP604 4.2 30.9 0.5 OE1 A:GLU192 4.3 41.9 1.0 O6 A:2PN606 4.3 62.8 0.5 N7 A:ANP604 4.3 33.3 0.5 N7 A:AMP605 4.3 33.2 0.5 O3A A:ANP604 4.4 32.3 0.5 O2P A:AMP605 4.4 32.0 0.5 O A:HOH727 4.4 55.4 1.0 N1 A:HFG603 4.4 30.3 1.0 O3 A:2PN606 4.5 41.4 0.5 O2G A:ANP604 4.5 41.6 0.5 OE1 A:GLU138 4.5 45.0 1.0 CD A:GLU192 4.7 43.6 1.0 C8 A:ANP604 4.8 32.3 0.5 C8 A:AMP605 4.8 32.3 0.5 OE2 A:GLU138 4.8 77.5 1.0 P2 A:2PN606 4.8 61.2 0.5 C2 A:HFG603 4.9 30.8 1.0 CD A:ARG190 4.9 26.7 1.0 CZ A:ARG190 4.9 28.7 1.0

D.M.Dranow, D.G.Conrady, D.D.Lorimer, P.S.Horanyi, T.E.Edwards. Crystal Structure of Prolyl-Trna Synthetase From Onchocerca Volvulus with Bound Halofuginone and Nucleotide To Be Published.