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Magnesium in PDB 6n9u: Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1)

Enzymatic activity of Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1)

All present enzymatic activity of Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1):
2.7.7.7; 3.6.4.12;

Other elements in 6n9u:

The structure of Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1) also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1) (pdb code 6n9u). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1), PDB code: 6n9u:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 6n9u

Go back to Magnesium Binding Sites List in 6n9u
Magnesium binding site 1 out of 2 in the Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1) within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Mg802

b:41.4
occ:1.00
OD2 H:ASP654 2.2 37.4 1.0
O H:ALA476 2.3 40.7 1.0
O2B H:TTP801 2.3 49.0 1.0
O1G H:TTP801 2.3 49.0 1.0
O2A H:TTP801 2.4 49.0 1.0
OD1 H:ASP475 2.5 39.7 1.0
OD2 H:ASP475 3.0 39.7 1.0
CG H:ASP475 3.0 39.7 1.0
CG H:ASP654 3.4 37.4 1.0
C H:ALA476 3.5 40.7 1.0
PB H:TTP801 3.6 49.0 1.0
PG H:TTP801 3.7 49.0 1.0
PA H:TTP801 3.7 49.0 1.0
O3B H:TTP801 4.0 49.0 1.0
O3A H:TTP801 4.0 49.0 1.0
OD1 H:ASP654 4.1 37.4 1.0
N H:ALA476 4.3 40.7 1.0
CB H:ASP654 4.3 37.4 1.0
N H:SER477 4.4 44.5 1.0
C5' H:TTP801 4.4 49.0 1.0
CA H:SER477 4.4 44.5 1.0
CB H:ASP475 4.5 39.7 1.0
O3G H:TTP801 4.5 49.0 1.0
CA H:ALA476 4.5 40.7 1.0
O5' H:TTP801 4.7 49.0 1.0
O2G H:TTP801 4.7 49.0 1.0
O1A H:TTP801 4.7 49.0 1.0
O1B H:TTP801 4.8 49.0 1.0
C H:ASP475 4.8 39.7 1.0
N H:GLY478 5.0 46.4 1.0

Magnesium binding site 2 out of 2 in 6n9u

Go back to Magnesium Binding Sites List in 6n9u
Magnesium binding site 2 out of 2 in the Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Bacteriophage T7 Lagging-Strand Dna Polymerase (D5A/E7A) Interacting with Primase Domains of Two GP4 Subunits Bound to An Rna/Dna Hybrid and Dttp (From LAGS1) within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Mg803

b:19.8
occ:1.00
O H:HIS59 3.6 35.7 1.0
OD2 H:ASP65 4.2 36.2 1.0
OD2 H:ASP174 4.4 43.9 1.0
C H:HIS59 4.7 35.7 1.0
O H:ILE6 4.8 35.1 1.0
CG2 H:ILE6 4.9 35.1 1.0

Reference:

Y.Gao, Y.Cui, T.Fox, S.Lin, H.Wang, N.De Val, Z.H.Zhou, W.Yang. Structures and Operating Principles of the Replisome. Science V. 363 2019.
ISSN: ESSN 1095-9203
PubMed: 30679383
DOI: 10.1126/SCIENCE.AAV7003
Page generated: Tue Oct 1 12:36:25 2024

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