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Atomistry » Magnesium » PDB 6t2c-6tfk » 6t5j | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 6t2c-6tfk » 6t5j » |
Magnesium in PDB 6t5j: Structure of NUDT15 in Complex with Inhibitor TH1760Enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH1760
All present enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH1760:
3.6.1.9; Protein crystallography data
The structure of Structure of NUDT15 in Complex with Inhibitor TH1760, PDB code: 6t5j
was solved by
M.Carter,
D.Rehling,
M.Desroses,
S.M.Zhang,
A.Hagenkort,
N.C.K.Valerie,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6t5j:
The structure of Structure of NUDT15 in Complex with Inhibitor TH1760 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of NUDT15 in Complex with Inhibitor TH1760
(pdb code 6t5j). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of NUDT15 in Complex with Inhibitor TH1760, PDB code: 6t5j: Jump to Magnesium binding site number: 1; 2; 3; 4; Magnesium binding site 1 out of 4 in 6t5jGo back to![]() ![]()
Magnesium binding site 1 out
of 4 in the Structure of NUDT15 in Complex with Inhibitor TH1760
![]() Mono view ![]() Stereo pair view
Magnesium binding site 2 out of 4 in 6t5jGo back to![]() ![]()
Magnesium binding site 2 out
of 4 in the Structure of NUDT15 in Complex with Inhibitor TH1760
![]() Mono view ![]() Stereo pair view
Magnesium binding site 3 out of 4 in 6t5jGo back to![]() ![]()
Magnesium binding site 3 out
of 4 in the Structure of NUDT15 in Complex with Inhibitor TH1760
![]() Mono view ![]() Stereo pair view
Magnesium binding site 4 out of 4 in 6t5jGo back to![]() ![]()
Magnesium binding site 4 out
of 4 in the Structure of NUDT15 in Complex with Inhibitor TH1760
![]() Mono view ![]() Stereo pair view
Reference:
S.M.Zhang,
M.Desroses,
A.Hagenkort,
N.C.K.Valerie,
D.Rehling,
M.Carter,
O.Wallner,
T.Koolmeister,
A.Throup,
A.S.Jemth,
I.Almlof,
O.Loseva,
T.Lundback,
H.Axelsson,
S.Regmi,
A.Sarno,
A.Kramer,
L.Pudelko,
L.Brautigam,
A.Rasti,
M.Gottmann,
E.Wiita,
J.Kutzner,
T.Schaller,
C.Kalderen,
A.Cazares-Korner,
B.D.G.Page,
R.Krimpenfort,
S.Eshtad,
M.Altun,
S.G.Rudd,
S.Knapp,
M.Scobie,
E.J.Homan,
U.W.Berglund,
P.Stenmark,
T.Helleday.
Development of A Chemical Probe Against NUDT15. Nat.Chem.Biol. V. 16 1120 2020.
Page generated: Tue Oct 1 18:41:37 2024
ISSN: ESSN 1552-4469 PubMed: 32690945 DOI: 10.1038/S41589-020-0592-Z |
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