Magnesium in PDB 6ujz: Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp

Enzymatic activity of Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp

All present enzymatic activity of Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp:
2.7.7.49; 2.7.7.7; 3.1.26.13;

Protein crystallography data

The structure of Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp, PDB code: 6ujz was solved by E.B.Lansdon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	47.34 / 2.56
*Space group*	C 2 2 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	168.277, 168.829, 102.548, 90.00, 90.00, 90.00
*R / R_free (%)*	18.5 / 23.6

Other elements in 6ujz:

The structure of Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp also contains other interesting chemical elements:

Fluorine

(F)

1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp (pdb code 6ujz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp, PDB code: 6ujz:

Magnesium binding site 1 out of 1 in 6ujz

Go back to

Magnesium Binding Sites List in 6ujz

Magnesium binding site 1 out of 1 in the Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Hiv-1 Wild-Type Reverse Transcriptase-Dna Complex with (+)-Ftc-Tp within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mg603 b:41.6 occ:1.00	OD2	A:ASP110	1.9	53.4	1.0
	OAD	A:N8G604	2.0	48.2	1.0
	OAC	A:N8G604	2.1	58.5	1.0
	O	A:VAL111	2.1	48.8	1.0
	OAI	A:N8G604	2.2	51.7	1.0
	OD2	A:ASP185	2.3	53.8	1.0
	CG	A:ASP110	2.9	53.6	1.0
	PBB	A:N8G604	3.2	52.0	1.0
	OD1	A:ASP110	3.3	63.7	1.0
	PAZ	A:N8G604	3.3	51.4	1.0
	C	A:VAL111	3.3	50.2	1.0
	CG	A:ASP185	3.5	49.2	1.0
	PBA	A:N8G604	3.5	48.1	1.0
	OAQ	A:N8G604	3.6	49.6	1.0
	OAR	A:N8G604	3.7	49.9	1.0
	OD1	A:ASP185	4.0	46.2	1.0
	NZ	A:LYS220	4.0	61.1	1.0
	N	A:VAL111	4.1	44.7	1.0
	CAL	A:N8G604	4.2	46.5	1.0
	CB	A:ASP110	4.2	44.8	1.0
	N	A:GLY112	4.3	51.1	1.0
	CA	A:VAL111	4.3	47.6	1.0
	OAO	A:N8G604	4.3	48.3	1.0
	OAF	A:N8G604	4.3	62.3	1.0
	CA	A:GLY112	4.3	47.4	1.0
	C	A:ASP110	4.4	48.0	1.0
	N	A:ASP113	4.4	53.5	1.0
	OAH	A:N8G604	4.5	49.5	1.0
	OAG	A:N8G604	4.6	61.7	1.0
	OAE	A:N8G604	4.7	56.9	1.0
	CB	A:ASP185	4.7	48.3	1.0
	C	A:GLY112	4.7	50.8	1.0
	N	A:ALA114	4.7	51.3	1.0
	CB	A:ALA114	4.7	51.3	1.0
	CA	A:ASP110	4.8	49.5	1.0
	O	A:ASP110	4.9	50.4	1.0
	CB	A:VAL111	4.9	45.0	1.0
	CE	A:LYS220	4.9	58.8	1.0

Reference:

M.Hung, E.J.Tokarsky, L.Lagpacan, L.Zhang, Z.Suo, E.B.Lansdon. Elucidating Molecular Interactions of L-Nucleotides with Hiv-1 Reverse Transcriptase and Mechanism of M184V-Caused Drug Resistance Commun Biol V. 2 2019.
ISSN: ESSN 2399-3642
DOI: 10.1038/S42003-019-0706-X

Page generated: Wed Aug 13 18:35:30 2025

Last articles

Na in 2X2V
Na in 2X0R
Na in 2X2F
Na in 2X2E
Na in 2X1Z
Na in 2X20
Na in 2X21
Na in 2X0A
Na in 2X0I
Na in 2WYV

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy