Magnesium in PDB 6v22: Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex

The structure of Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex also contains other interesting chemical elements:

Potassium	(K)	4 atoms
Calcium	(Ca)	8 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex (pdb code 6v22). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex, PDB code: 6v22:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1101 b:62.1 occ:1.00 OE2 A:GLU399 2.3 62.0 1.0 OE2 A:GLU374 3.2 69.2 1.0 CD A:GLU399 3.3 62.0 1.0 OE1 A:GLU374 3.5 69.2 1.0 CD A:GLU374 3.5 69.2 1.0 CG A:GLU399 3.8 62.0 1.0 O A:THR396 3.9 66.6 1.0 OE1 A:GLU399 4.5 62.0 1.0 CG A:GLU374 4.6 69.2 1.0 C A:THR396 4.7 66.6 1.0 OD1 D:ASN172 4.8 83.0 1.0

Magnesium binding site 2 out of 4 in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1106 b:58.8 occ:1.00 OE2 B:GLU399 2.3 61.7 1.0 OE2 B:GLU374 3.2 69.1 1.0 CD B:GLU399 3.3 61.7 1.0 OE1 B:GLU374 3.5 69.1 1.0 CD B:GLU374 3.5 69.1 1.0 CG B:GLU399 3.8 61.7 1.0 O B:THR396 3.9 66.5 1.0 OE1 B:GLU399 4.5 61.7 1.0 CG B:GLU374 4.6 69.1 1.0 C B:THR396 4.7 66.5 1.0 OD1 A:ASN172 4.8 84.7 1.0

Magnesium binding site 3 out of 4 in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1106 b:63.0 occ:1.00 OE2 C:GLU399 2.3 61.9 1.0 OE2 C:GLU374 3.2 68.8 1.0 CD C:GLU399 3.3 61.9 1.0 OE1 C:GLU374 3.5 68.8 1.0 CD C:GLU374 3.5 68.8 1.0 CG C:GLU399 3.8 61.9 1.0 O C:THR396 3.9 66.2 1.0 OE1 C:GLU399 4.5 61.9 1.0 CG C:GLU374 4.6 68.8 1.0 C C:THR396 4.7 66.2 1.0 OD1 B:ASN172 4.8 83.0 1.0

Magnesium binding site 4 out of 4 in the Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Structure of CA2+-Bound HSSLO1-BETA4 Channel Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1106 b:59.1 occ:1.00 OE2 D:GLU399 2.3 61.8 1.0 OE2 D:GLU374 3.2 68.9 1.0 CD D:GLU399 3.3 61.8 1.0 OE1 D:GLU374 3.5 68.9 1.0 CD D:GLU374 3.5 68.9 1.0 CG D:GLU399 3.8 61.8 1.0 O D:THR396 3.9 66.1 1.0 OE1 D:GLU399 4.5 61.8 1.0 CG D:GLU374 4.6 68.9 1.0 C D:THR396 4.7 66.1 1.0 OD1 C:ASN172 4.8 84.7 1.0

X.Tao, R.Mackinnon. Molecular Structures of the Human SLO1 K+Channel in Complex with Beta 4. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 31815672
DOI: 10.7554/ELIFE.51409