Magnesium in PDB 7bdp: 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017

Enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017

All present enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017:
5.2.1.8;

Protein crystallography data

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017, PDB code: 7bdp was solved by M.Wolter, L.V.Dijck, P.J.Cossar, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	41.63 / 1.75
*Space group*	C 2 2 2₁
*Cell size a, b, c (Å), α, β, γ (°)*	81.989, 111.691, 62.463, 90, 90, 90
*R / R_free (%)*	17.3 / 21.7

Other elements in 7bdp:

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 (pdb code 7bdp). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017, PDB code: 7bdp:

Magnesium binding site 1 out of 1 in 7bdp

Go back to

Magnesium Binding Sites List in 7bdp

Magnesium binding site 1 out of 1 in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mg302 b:14.1 occ:1.00	OE1	A:GLU35	2.2	19.3	1.0
	O	A:HOH458	2.2	28.6	1.0
	O	A:GLU110	2.3	14.0	1.0
	O	A:HOH548	2.4	23.9	1.0
	CD	A:GLU35	2.8	25.7	1.0
	OE2	A:GLU35	2.9	27.8	1.0
	C	A:GLU110	3.5	14.4	1.0
	N	A:GLY112	3.9	18.1	1.0
	CG	A:GLU35	4.3	16.0	1.0
	OE1	A:GLU110	4.3	33.3	1.0
	CA	A:GLU110	4.4	9.5	1.0
	O	A:HOH622	4.4	29.2	1.0
	N	A:ALA111	4.4	10.3	1.0
	CA	A:GLY112	4.5	23.0	1.0
	CA	A:ALA111	4.5	10.5	1.0
	CB	A:GLU110	4.6	12.9	1.0
	O	A:HOH583	4.6	31.9	1.0
	C	A:ALA111	4.6	15.2	1.0

Reference:

P.J.Cossar, M.Wolter, L.Van Dijck, D.Valenti, L.M.Levy, C.Ottmann, L.Brunsveld. Reversible Covalent Imine-Tethering For Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc. 2021.
ISSN: ESSN 1520-5126
PubMed: 34047554
DOI: 10.1021/JACS.1C03035

Page generated: Wed Oct 2 10:25:36 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy