Magnesium in PDB 7c40: Mggdp Bound Kras G12V

The structure of Mggdp Bound Kras G12V, PDB code: 7c40 was solved by C.W.Han, M.S.Jeong, S.B.Jang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.02 / 2.52
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	82.547, 82.547, 40.804, 90, 90, 120
R / Rfree (%)	17.5 / 22.6

The binding sites of Magnesium atom in the Mggdp Bound Kras G12V (pdb code 7c40). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mggdp Bound Kras G12V, PDB code: 7c40:

Magnesium binding site 1 out of 1 in the Mggdp Bound Kras G12V


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mggdp Bound Kras G12V within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1001 b:26.3 occ:1.00 O A:HOH1106 1.9 32.6 1.0 O A:HOH1109 1.9 26.9 1.0 OG A:SER17 2.2 26.7 1.0 O3B A:GDP1002 2.5 28.9 1.0 O A:HOH1102 2.5 36.5 1.0 CB A:SER17 3.5 26.8 1.0 PB A:GDP1002 3.8 26.5 1.0 O1B A:GDP1002 4.0 24.3 1.0 OD2 A:ASP57 4.0 42.9 1.0 O A:ASP33 4.0 30.4 1.0 O A:ILE36 4.1 43.4 1.0 CA A:PRO34 4.1 29.4 1.0 O A:PRO34 4.2 45.2 1.0 N A:SER17 4.4 27.1 1.0 CD1 A:TYR32 4.4 22.2 1.0 C A:PRO34 4.4 40.6 1.0 O1A A:GDP1002 4.4 20.8 1.0 CA A:SER17 4.5 29.9 1.0 O A:THR58 4.5 39.0 1.0 CB A:ALA59 4.6 52.3 1.0 O A:TYR32 4.6 37.4 1.0 OD1 A:ASP57 4.7 47.3 1.0 C A:ASP33 4.7 31.9 1.0 O2B A:GDP1002 4.7 19.2 1.0 CG A:ASP57 4.7 38.8 1.0 N A:PRO34 4.8 34.1 1.0 O3A A:GDP1002 4.8 22.9 1.0 CE1 A:TYR32 5.0 21.8 1.0 PA A:GDP1002 5.0 24.4 1.0

C.W.Han, M.S.Jeong, S.C.Ha, S.B.Jang. A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic Kras Mutants. Cancers (Basel) V. 12 2020.
ISSN: ESSN 2072-6694
PubMed: 32486141
DOI: 10.3390/CANCERS12061412