Magnesium in PDB 7cmj: Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt)

All present enzymatic activity of Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt):
2.4.2.8;

The structure of Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt), PDB code: 7cmj was solved by P.S.Parihar, J.V.Pratap, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.37 / 2.76
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	80.8, 80.8, 344.321, 90, 90, 120
R / Rfree (%)	18.1 / 22.5

The structure of Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt) also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Barium	(Ba)	2 atoms

The binding sites of Magnesium atom in the Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt) (pdb code 7cmj). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt), PDB code: 7cmj:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:53.5 occ:1.00 OD1 A:ASP185 2.2 50.4 1.0 O3 A:PO4303 2.2 39.5 1.0 O A:HOH403 2.3 57.9 1.0 O A:HOH422 2.3 62.0 1.0 O A:HOH418 2.5 48.2 1.0 CG A:ASP185 3.2 47.3 1.0 P A:PO4303 3.4 44.2 1.0 OD2 A:ASP185 3.6 52.3 1.0 O A:HOH429 3.6 49.8 1.0 O4 A:PO4303 3.8 53.6 1.0 O1 A:PO4303 3.9 48.8 1.0 NH2 A:ARG191 4.4 32.9 1.0 O A:HOH416 4.4 55.2 1.0 O A:HOH414 4.5 51.9 1.0 CB A:ASP185 4.5 42.3 1.0 O A:ASP185 4.6 40.6 1.0 O2 A:PO4303 4.7 35.5 1.0 NH1 A:ARG191 4.8 55.8 1.0 N A:ASP185 5.0 47.0 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg302 b:66.6 occ:1.00 O B:HOH401 2.0 63.0 1.0 OD2 B:ASP185 2.3 45.9 1.0 O B:HOH435 2.6 66.5 1.0 O B:HOH421 2.6 54.7 1.0 O4 B:PO4304 2.6 35.8 1.0 O B:HOH416 3.2 47.7 1.0 CG B:ASP185 3.4 47.4 1.0 O B:HOH413 3.6 63.0 1.0 O B:HOH426 3.7 70.4 1.0 OD1 B:ASP185 3.7 40.6 1.0 P B:PO4304 3.9 49.6 1.0 O B:ASP185 4.2 56.7 1.0 O3 B:PO4304 4.3 60.7 1.0 O1 B:PO4304 4.5 59.3 1.0 CB B:ASP185 4.7 50.4 1.0 O B:HOH414 4.7 50.9 1.0 C B:ASP185 4.8 49.6 1.0 NH2 B:ARG191 4.8 36.2 1.0 N B:ASP185 4.9 43.3 1.0

P.S.Parihar, J.V.Pratap. Crystal Structure of L.Donovani Hypoxanthine-Guanine Phosphoribosyl Transferase (Hgprt) To Be Published.