Magnesium in PDB 7dsj: Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg

All present enzymatic activity of Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg:
2.4.2.18;

The structure of Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg, PDB code: 7dsj was solved by X.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.99 / 2.44
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	78.328, 89.488, 110.299, 90, 90, 90
R / Rfree (%)	18 / 24.2

The binding sites of Magnesium atom in the Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg (pdb code 7dsj). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg, PDB code: 7dsj:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:35.4 occ:1.00 O1A A:PRP401 2.1 41.8 1.0 O A:HOH524 2.1 46.8 1.0 OE2 A:GLU259 2.2 52.0 1.0 O A:HOH521 2.3 39.2 1.0 O3B A:PRP401 2.4 43.4 1.0 OG A:SER121 2.5 45.0 1.0 CD A:GLU259 3.1 53.4 1.0 CB A:SER121 3.2 38.0 1.0 PA A:PRP401 3.2 44.8 1.0 OE1 A:GLU259 3.4 52.6 1.0 PB A:PRP401 3.5 51.1 1.0 O3A A:PRP401 3.6 50.3 1.0 O1 A:PRP401 3.9 57.9 1.0 N A:GLY109 3.9 31.3 1.0 O A:ASP258 4.1 31.1 1.0 O1B A:PRP401 4.2 51.6 1.0 N A:SER121 4.2 39.8 1.0 CA A:SER121 4.2 37.9 1.0 O A:HOH538 4.3 32.3 1.0 OD1 A:ASP258 4.3 29.4 1.0 CA A:GLY109 4.3 31.5 1.0 OD2 A:ASP258 4.4 37.0 1.0 CG A:GLU259 4.5 46.9 1.0 O A:HOH544 4.5 42.9 1.0 O2A A:PRP401 4.6 40.0 1.0 CG A:ASP258 4.6 32.9 1.0 C A:VAL108 4.7 36.7 1.0 C1 A:PRP401 4.7 64.1 1.0 O2B A:PRP401 4.7 46.7 1.0 CG1 A:VAL120 4.8 53.4 1.0 CB A:GLU259 4.9 38.6 1.0 CA A:VAL108 5.0 34.1 1.0

Magnesium binding site 2 out of 2 in the Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae in Complex with Prpp and Mg within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg402 b:60.0 occ:1.00 O B:HOH511 2.0 51.5 1.0 O2A B:PRP401 2.2 55.7 1.0 O B:HOH523 2.3 55.6 1.0 OE2 B:GLU259 2.3 50.3 1.0 O2B B:PRP401 2.4 50.6 1.0 OG B:SER121 2.6 36.8 1.0 OE1 B:GLU259 2.8 59.3 1.0 CD B:GLU259 2.9 54.0 1.0 CB B:SER121 3.3 31.6 1.0 PA B:PRP401 3.3 61.0 1.0 PB B:PRP401 3.5 69.0 1.0 O3A B:PRP401 3.5 69.3 1.0 O1 B:PRP401 4.0 77.5 1.0 O3B B:PRP401 4.0 66.4 1.0 OD1 B:ASP258 4.1 34.3 1.0 N B:SER121 4.1 29.2 1.0 O B:HOH531 4.2 45.0 1.0 N B:GLY109 4.2 29.9 1.0 CA B:SER121 4.2 29.6 1.0 O B:ASP258 4.3 39.6 1.0 CG B:GLU259 4.4 51.6 1.0 O B:HOH566 4.4 50.0 1.0 OD2 B:ASP258 4.6 36.0 1.0 CG B:ASP258 4.6 35.2 1.0 C1 B:PRP401 4.6 79.4 1.0 CA B:GLY109 4.6 31.8 1.0 O1A B:PRP401 4.6 65.5 1.0 CG1 B:VAL120 4.8 40.6 1.0 O1B B:PRP401 4.8 47.5 1.0 O B:HOH506 4.9 45.8 1.0 O4 B:PRP401 5.0 81.4 1.0

X.Wu, M.Zhang, Z.Kuang, J.Yue, L.Xue, M.Zhu, Z.Zhu, M.H.Khan, L.Niu. Crystal Structures of Anthranilate Phosphoribosyltransferase From Saccharomyces Cerevisiae. Acta Crystallogr.,Sect.F V. 77 61 2021.
ISSN: ESSN 2053-230X
PubMed: 33682790
DOI: 10.1107/S2053230X21001989