Atomistry » Magnesium » PDB 7o11-7o6a » 7o5g
Atomistry »
  Magnesium »
    PDB 7o11-7o6a »
      7o5g »

Magnesium in PDB 7o5g: 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164

Protein crystallography data

The structure of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164, PDB code: 7o5g was solved by M.Wolter, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.64 / 1.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 82.672, 112.33, 62.688, 90, 90, 90
R / Rfree (%) 18.7 / 22

Other elements in 7o5g:

The structure of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164 also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164 (pdb code 7o5g). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164, PDB code: 7o5g:

Magnesium binding site 1 out of 1 in 7o5g

Go back to Magnesium Binding Sites List in 7o5g
Magnesium binding site 1 out of 1 in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-164 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg306

b:7.1
occ:0.51
O A:HOH524 2.1 27.4 1.0
OE1 A:GLU2 2.4 13.2 1.0
O A:HOH463 2.5 12.1 1.0
CD A:GLU2 3.4 13.8 1.0
OE2 A:GLU2 3.8 11.7 1.0
O A:HOH559 4.3 9.6 1.0
O A:HOH649 4.5 10.8 1.0
CG A:GLU2 4.7 9.5 1.0
CA A:GLU2 4.9 10.6 1.0
O A:HOH464 5.0 20.5 1.0

Reference:

M.Wolter, D.Valenti, P.J.Cossar, S.Hristeva, L.M.Levy, T.Genski, T.Hoffmann, L.Brunsveld, D.Tzalis, C.Ottmann. An Exploration of Chemical Properties Required For Cooperative Stabilization of the 14-3-3 Interaction with Nf-Kappa B-Utilizing A Reversible Covalent Tethering Approach. J.Med.Chem. 2021.
ISSN: ISSN 0022-2623
PubMed: 34076416
DOI: 10.1021/ACS.JMEDCHEM.1C00401
Page generated: Thu Oct 3 02:33:17 2024

Last articles

Ca in 7NRK
Ca in 7NPG
Ca in 7NPB
Ca in 7NN9
Ca in 7NMX
Ca in 7NN2
Ca in 7NIT
Ca in 7NMH
Ca in 7NM3
Ca in 7NLM
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy