Magnesium in PDB 7pw8: Human SMG1-8-9 Kinase Complex Bound to Amppnp

All present enzymatic activity of Human SMG1-8-9 Kinase Complex Bound to Amppnp:
2.7.11.1;

The binding sites of Magnesium atom in the Human SMG1-8-9 Kinase Complex Bound to Amppnp (pdb code 7pw8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human SMG1-8-9 Kinase Complex Bound to Amppnp, PDB code: 7pw8:

Magnesium binding site 1 out of 1 in the Human SMG1-8-9 Kinase Complex Bound to Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human SMG1-8-9 Kinase Complex Bound to Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg602 b:8.9 occ:1.00 OG C:SER218 2.1 2.6 1.0 OG1 C:THR253 2.1 5.7 1.0 O1G C:ATP601 2.5 8.9 1.0 O3B C:ATP601 2.6 8.9 1.0 CB C:THR253 2.9 5.7 1.0 PG C:ATP601 3.0 8.9 1.0 CB C:SER218 3.4 2.6 1.0 O3G C:ATP601 3.7 8.9 1.0 PB C:ATP601 3.8 8.9 1.0 N C:THR253 3.8 5.7 1.0 CG2 C:THR253 3.9 5.7 1.0 O3A C:ATP601 3.9 8.9 1.0 CA C:THR253 4.0 5.7 1.0 N C:SER218 4.0 2.6 1.0 O2B C:ATP601 4.1 8.9 1.0 OD2 C:ASP269 4.2 4.5 1.0 CA C:SER218 4.2 2.6 1.0 O2G C:ATP601 4.3 8.9 1.0 OD1 C:ASP269 4.5 4.5 1.0 O1A C:ATP601 4.5 8.9 1.0 O C:ARG239 4.6 6.8 1.0 O C:THR270 4.7 8.9 1.0 CE C:LYS217 4.7 2.6 1.0 CG C:ASP269 4.8 4.5 1.0 PA C:ATP601 4.9 8.9 1.0 CB C:LYS217 4.9 2.6 1.0 NZ C:LYS217 5.0 2.6 1.0 C C:GLN252 5.0 6.4 1.0

L.M.Langer, F.Bonneau, Y.Gat, E.Conti. Cryo-Em Reconstructions of Inhibitor-Bound SMG1 Kinase Reveal An Autoinhibitory State Dependent on SMG8. Elife V. 10 2021.
ISSN: ESSN 2050-084X
PubMed: 34698635
DOI: 10.7554/ELIFE.72353