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Atomistry » Magnesium » PDB 7reh-7rr9 » 7rp3 » |
Magnesium in PDB 7rp3: Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 ClampEnzymatic activity of Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp
All present enzymatic activity of Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp:
3.6.5.2; Protein crystallography data
The structure of Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp, PDB code: 7rp3
was solved by
A.Oh,
C.Tam,
W.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7rp3:
The structure of Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp
(pdb code 7rp3). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp, PDB code: 7rp3: Magnesium binding site 1 out of 1 in 7rp3Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Gne-1952 Alkylated Kras G12C in Complex with 2H11 Clamp
![]() Mono view ![]() Stereo pair view
Reference:
C.W.Davies,
A.J.Oh,
R.Mroue,
M.Steffek,
J.M.Bruning,
Y.Xiao,
S.Feng,
S.Jayakar,
E.Chan,
V.Arumugam,
S.C.Uribe,
J.Drummond,
A.Frommlet,
C.Lu,
Y.Franke,
M.Merchant,
H.Koeppen,
J.G.Quinn,
S.Malhotra,
S.Do,
L.Gazzard,
H.E.Purkey,
J.Rudolph,
M.M.Mulvihill,
J.T.Koerber,
W.Wang,
M.Evangelista.
Conformation-Locking Antibodies For the Discovery and Characterization of Kras Inhibitors. Nat.Biotechnol. V. 40 769 2022.
Page generated: Thu Oct 3 08:04:59 2024
ISSN: ISSN 1087-0156 PubMed: 34992247 DOI: 10.1038/S41587-021-01126-9 |
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