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Atomistry » Magnesium » PDB 7tf9-7tlk » 7tiu » |
Magnesium in PDB 7tiu: Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46Enzymatic activity of Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46
All present enzymatic activity of Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46:
3.4.22.69; Protein crystallography data
The structure of Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46, PDB code: 7tiu
was solved by
F.Forouhar,
H.Liu,
S.Iketani,
A.Zack,
N.Khanizeman,
E.Bednarova,
B.Fowler,
S.J.Hong,
H.Mohri,
M.S.Nair,
Y.Huang,
N.E.S.Tay,
S.Lee,
C.Karan,
S.J.Resnick,
C.Quinn,
W.Li,
H.Shion,
C.Jurtschenko,
M.A.Lauber,
T.Mcdonald,
M.E.Stokes,
B.Hurst,
T.Rovis,
A.Chavez,
D.D.Ho,
B.R.Stockwell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tiu:
The structure of Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46
(pdb code 7tiu). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46, PDB code: 7tiu: Magnesium binding site 1 out of 1 in 7tiuGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Sars-Cov-2 3CL in Complex with Inhibitor EB46
![]() Mono view ![]() Stereo pair view
Reference:
H.Liu,
S.Iketani,
A.Zask,
N.Khanizeman,
E.Bednarova,
F.Forouhar,
B.Fowler,
S.J.Hong,
H.Mohri,
M.S.Nair,
Y.Huang,
N.E.S.Tay,
S.Lee,
C.Karan,
S.J.Resnick,
C.Quinn,
W.Li,
H.Shion,
X.Xia,
J.D.Daniels,
M.Bartolo-Cruz,
M.Farina,
P.Rajbhandari,
C.Jurtschenko,
M.A.Lauber,
T.Mcdonald,
M.E.Stokes,
B.L.Hurst,
T.Rovis,
A.Chavez,
D.D.Ho,
B.R.Stockwell.
Development of Optimized Drug-Like Small Molecule Inhibitors of the Sars-Cov-2 3CL Protease For Treatment of Covid-19. Nat Commun V. 13 1891 2022.
Page generated: Thu Oct 3 09:18:20 2024
ISSN: ESSN 2041-1723 PubMed: 35393402 DOI: 10.1038/S41467-022-29413-2 |
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