Magnesium in PDB 7zk6: ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac

All present enzymatic activity of ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac:
7.6.2.1; 7.6.2.2;

The binding sites of Magnesium atom in the ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac (pdb code 7zk6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac, PDB code: 7zk6:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2002 b:26.2 occ:1.00 O A:HOH2102 2.1 35.0 1.0 OG A:SER430 2.1 32.9 1.0 OE1 A:GLN471 2.1 31.9 1.0 O2B A:ATP2001 2.1 39.6 1.0 O A:HOH2104 2.1 24.8 1.0 O1G A:ATP2001 2.2 39.6 1.0 O3B A:ATP2001 3.0 39.6 1.0 CB A:SER430 3.0 32.9 1.0 PB A:ATP2001 3.1 39.6 1.0 PG A:ATP2001 3.1 39.6 1.0 CD A:GLN471 3.2 31.9 1.0 O1A A:ATP2001 3.3 39.6 1.0 NE2 A:GLN471 3.7 31.9 1.0 O3A A:ATP2001 3.7 39.6 1.0 OD2 A:ASP551 4.0 40.1 1.0 PA A:ATP2001 4.1 39.6 1.0 N A:GLY1174 4.1 28.5 1.0 O3G A:ATP2001 4.2 39.6 1.0 O2G A:ATP2001 4.2 39.6 1.0 CA A:SER430 4.2 32.9 1.0 CB A:SER1173 4.3 24.5 1.0 N A:SER430 4.3 32.9 1.0 O1B A:ATP2001 4.4 39.6 1.0 CG A:GLN471 4.5 31.9 1.0 CA A:SER1173 4.5 24.5 1.0 CB A:GLN471 4.6 31.9 1.0 OD1 A:ASP551 4.7 40.1 1.0 CG A:ASP551 4.8 40.1 1.0 O2A A:ATP2001 4.9 39.6 1.0 C A:SER1173 4.9 24.5 1.0

Magnesium binding site 2 out of 2 in the ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2004 b:29.6 occ:1.00 O2B A:ATP2003 2.0 25.2 1.0 O A:HOH2101 2.1 33.7 1.0 OE1 A:GLN1114 2.1 30.2 1.0 O A:HOH2103 2.1 27.3 1.0 OG A:SER1073 2.1 32.9 1.0 O2G A:ATP2003 2.2 25.2 1.0 O3B A:ATP2003 3.0 25.2 1.0 PB A:ATP2003 3.1 25.2 1.0 CD A:GLN1114 3.1 30.2 1.0 CB A:SER1073 3.2 32.9 1.0 PG A:ATP2003 3.2 25.2 1.0 NE2 A:GLN1114 3.5 30.2 1.0 O1A A:ATP2003 3.7 25.2 1.0 O3A A:ATP2003 3.8 25.2 1.0 OD2 A:ASP1196 4.1 37.4 1.0 OG A:SER528 4.1 27.3 1.0 N A:GLY529 4.1 28.4 1.0 O3G A:ATP2003 4.2 25.2 1.0 O1G A:ATP2003 4.2 25.2 1.0 OD1 A:ASP1196 4.3 37.4 1.0 N A:SER1073 4.3 32.9 1.0 O1B A:ATP2003 4.3 25.2 1.0 CA A:SER1073 4.3 32.9 1.0 PA A:ATP2003 4.3 25.2 1.0 CG A:GLN1114 4.4 30.2 1.0 CG A:ASP1196 4.6 37.4 1.0 CB A:GLN1114 4.6 30.2 1.0 CA A:GLY529 4.8 28.4 1.0

T.Gewering, D.Waghray, K.Parey, D.Januliene, I.Urbatsch, A.Moeller, Q.Zhang. ABCB1 L335C Mutant (MABCB1) in the Outward Facing State Bound to 2 Molecules of Aac To Be Published.