Magnesium in PDB 8asd: Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation]

All present enzymatic activity of Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation]:
2.7.7.48;

The binding sites of Magnesium atom in the Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation] (pdb code 8asd). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation], PDB code: 8asd:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation]


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation] within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2101 b:18.9 occ:1.00 OD1 A:ASP1127 2.1 25.3 1.0 O G:HOH101 2.2 23.4 1.0 O3' G:C13 2.4 27.1 1.0 OD1 A:ASP985 2.4 21.6 1.0 OD1 A:ASP1126 2.6 26.8 1.0 O2A A:2KH2104 2.7 27.1 1.0 CG A:ASP1127 3.1 25.3 1.0 OD2 A:ASP1126 3.2 26.8 1.0 CG A:ASP1126 3.2 26.8 1.0 OD2 A:ASP1127 3.5 25.3 1.0 CG A:ASP985 3.5 21.6 1.0 C3' G:C13 3.7 27.1 1.0 PA A:2KH2104 3.7 27.1 1.0 MG A:MG2102 3.9 27.1 1.0 O5' A:2KH2104 4.0 27.1 1.0 O1A A:2KH2104 4.0 27.1 1.0 O G:HOH102 4.1 42.4 1.0 OD2 A:ASP985 4.1 21.6 1.0 C5' A:2KH2104 4.2 27.1 1.0 C4' G:C13 4.2 27.1 1.0 C5' G:C13 4.4 27.1 1.0 CB A:ASP1127 4.4 25.3 1.0 N A:ASP1127 4.5 25.3 1.0 CB A:ASP1126 4.6 26.8 1.0 CB A:ASP985 4.7 21.6 1.0 CA A:ASP1127 4.8 25.3 1.0 C A:ASP1126 4.8 26.8 1.0 O2' G:C13 4.8 27.1 1.0 C2' G:C13 4.8 27.1 1.0 O5' G:C13 5.0 27.1 1.0

Magnesium binding site 2 out of 3 in the Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation]


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation] within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2102 b:27.1 occ:1.00 O3G A:2KH2104 2.1 27.1 1.0 O1B A:2KH2104 2.2 27.1 1.0 O2A A:2KH2104 2.3 27.1 1.0 OD2 A:ASP1126 2.3 26.8 1.0 O A:ALA986 2.4 21.4 1.0 OD2 A:ASP985 2.5 21.6 1.0 PB A:2KH2104 3.2 27.1 1.0 CG A:ASP985 3.3 21.6 1.0 PG A:2KH2104 3.4 27.1 1.0 PA A:2KH2104 3.5 27.1 1.0 OD1 A:ASP985 3.5 21.6 1.0 C A:ALA986 3.5 21.4 1.0 CG A:ASP1126 3.6 26.8 1.0 O3B A:2KH2104 3.6 27.1 1.0 N3A A:2KH2104 3.6 27.1 1.0 MG A:MG2101 3.9 18.9 1.0 N A:ALA986 3.9 21.4 1.0 O1G A:2KH2104 4.1 27.1 1.0 C5' A:2KH2104 4.2 27.1 1.0 NZ A:LYS1170 4.2 24.5 1.0 CA A:ALA986 4.3 21.4 1.0 OD1 A:ASP1126 4.3 26.8 1.0 O5' A:2KH2104 4.4 27.1 1.0 O2G A:2KH2104 4.5 27.1 1.0 O2B A:2KH2104 4.5 27.1 1.0 N A:LYS987 4.6 22.7 1.0 CB A:ASP1126 4.6 26.8 1.0 O1A A:2KH2104 4.6 27.1 1.0 N A:LYS988 4.6 26.0 1.0 CB A:ASP985 4.7 21.6 1.0 CE A:LYS1170 4.7 24.5 1.0 CB A:ALA986 4.8 21.4 1.0 CA A:LYS987 4.8 22.7 1.0 C A:ASP985 4.8 21.6 1.0 CB A:TRP989 4.9 27.1 1.0 N A:TRP989 4.9 27.1 1.0 O G:HOH101 5.0 23.4 1.0

Magnesium binding site 3 out of 3 in the Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation]


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the Sftsv L Protein Stalled at Late Elongation [Late- Elongation] within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2103 b:44.8 occ:1.00 OP1 E:A5 2.0 59.2 1.0 OE2 A:GLU126 2.1 39.0 1.0 CD A:GLU126 2.9 39.0 1.0 OE1 A:GLU126 3.2 39.0 1.0 P E:A5 3.3 59.2 1.0 O3' E:C4 3.8 66.3 1.0 CB A:ALA112 3.9 47.8 1.0 NE2 A:HIS80 3.9 39.3 1.0 O A:PHE127 3.9 35.0 1.0 OP2 E:A5 4.1 59.2 1.0 N A:ALA112 4.1 47.8 1.0 CG A:GLU126 4.2 39.0 1.0 N A:PHE127 4.3 35.0 1.0 CA A:ALA112 4.3 47.8 1.0 NZ A:LYS145 4.4 39.3 1.0 CE1 A:HIS80 4.4 39.3 1.0 O5' E:A5 4.5 59.2 1.0 O A:THR110 4.7 60.8 1.0 C A:PHE127 4.9 35.0 1.0 C5' E:A5 4.9 59.2 1.0 C A:PRO111 4.9 53.6 1.0 CD2 A:HIS80 4.9 39.3 1.0 OD1 A:ASP92 4.9 82.9 1.0

H.M.Williams, S.R.Thorkelsson, D.Vogel, M.Milewski, C.Busch, S.Cusack, K.Grunewald, E.R.J.Quemin, M.Rosenthal. Structural Insights Into Viral Genome Replication By the Severe Fever with Thrombocytopenia Syndrome Virus L Protein Nucleic Acids Res. 2023.
ISSN: ESSN 1362-4962
DOI: 10.1093/NAR/GKAC1249