Magnesium in PDB 8ayh: Structure of Complement C5 in Complex with Small Molecule Inhibitor and Cvf

The binding sites of Magnesium atom in the Structure of Complement C5 in Complex with Small Molecule Inhibitor and Cvf (pdb code 8ayh). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Complement C5 in Complex with Small Molecule Inhibitor and Cvf, PDB code: 8ayh:

Magnesium binding site 1 out of 1 in the Structure of Complement C5 in Complex with Small Molecule Inhibitor and Cvf


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Complement C5 in Complex with Small Molecule Inhibitor and Cvf within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg2000 b:32.4 occ:1.00 OD1 B:ASP542 2.1 41.4 1.0 OD1 B:ASP539 2.1 42.3 1.0 O B:VAL540 2.8 33.5 1.0 CG B:ASP542 2.8 41.4 1.0 O B:PRO516 2.8 36.2 1.0 OD2 B:ASP542 2.9 41.4 1.0 CG B:ASP539 3.3 42.3 1.0 OD2 B:ASP539 3.8 42.3 1.0 C B:PRO516 3.9 36.2 1.0 C B:VAL540 4.0 33.5 1.0 OE2 B:GLU603 4.0 51.7 1.0 CB B:PRO516 4.2 36.2 1.0 CB B:ASP542 4.2 41.4 1.0 N B:ASP542 4.3 41.4 1.0 CA B:PRO516 4.4 36.2 1.0 N B:VAL540 4.5 33.5 1.0 CB B:ASP539 4.5 42.3 1.0 OE1 B:GLU603 4.5 51.7 1.0 C B:ASP539 4.6 42.3 1.0 CD B:GLU603 4.6 51.7 1.0 CA B:ASP539 4.7 42.3 1.0 CA B:ASP542 4.7 41.4 1.0 C B:LYS541 4.8 37.1 1.0 CA B:LYS541 4.8 37.1 1.0 N B:LYS541 4.9 37.1 1.0 CA B:VAL540 4.9 33.5 1.0 N B:SER517 5.0 41.1 1.0

K.Jendza, M.Kato, M.Salcius, H.Srinivas, A.De Erkenez, A.Nguyen, D.Mclaughlin, C.Be, C.Wiesmann, J.Murphy, P.Bolduc, M.Mogi, J.Duca, A.Namil, M.Capparelli, V.Darsigny, E.Meredith, R.Tichkule, L.Ferrara, J.Heyder, F.Liu, P.A.Horton, M.J.Romanowski, M.Schirle, N.Mainolfi, K.Anderson, G.A.Michaud. A Small-Molecule Inhibitor of C5 Complement Protein. Nat.Chem.Biol. V. 15 666 2019.
ISSN: ESSN 1552-4469
PubMed: 31209353
DOI: 10.1038/S41589-019-0303-9