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Magnesium in PDB 8grd: Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg
Enzymatic activity of Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg
All present enzymatic activity of Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg:
1.1.1.41;
1.1.1.41;
Protein crystallography data
The structure of Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg, PDB code: 8grd
was solved by
X.Chen,
P.Sun,
J.Ding,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 23.31 / 2.70 |
| Space group | I 4 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 165.897, 165.897, 129.583, 90, 90, 90 |
| R / Rfree (%) | 19.4 / 24.2 |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg
(pdb code 8grd). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg, PDB code: 8grd:
In total only one binding site of Magnesium was determined in the Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg, PDB code: 8grd:
Magnesium binding site 1 out of 1 in 8grd
Go back to
Magnesium Binding Sites List in 8grd
Magnesium binding site 1 out
of 1 in the Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of A Constitutively Active Mutant of the Alpha Beta Heterodimer of Human IDH3 in Complex with Adp and Mg within 5.0Å range:
|
Reference:
X.Chen,
P.Sun,
Y.Liu,
S.Shen,
T.Ma,
J.Ding.
Structures of A Constitutively Active Mutant of Human IDH3 Reveal New Insights Into the Mechanisms of Allosteric Activation and the Catalytic Reaction. J.Biol.Chem. V. 298 02695 2022.
ISSN: ESSN 1083-351X
PubMed: 36375638
DOI: 10.1016/J.JBC.2022.102695
Page generated: Fri Oct 4 03:55:04 2024
ISSN: ESSN 1083-351X
PubMed: 36375638
DOI: 10.1016/J.JBC.2022.102695
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