Magnesium in PDB 8p09: 48S Late-Stage Initiation Complex with Non Methylated Mrna

All present enzymatic activity of 48S Late-Stage Initiation Complex with Non Methylated Mrna:
4.2.99.18;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 80; Page 9, Binding sites: 81 - 90; Page 10, Binding sites: 91 - 100; Page 11, Binding sites: 101 - 110; Page 12, Binding sites: 111 - 120; Page 13, Binding sites: 121 - 130; Page 14, Binding sites: 131 - 140; Page 15, Binding sites: 141 - 150; Page 16, Binding sites: 151 - 160; Page 17, Binding sites: 161 - 170; Page 18, Binding sites: 171 - 180; Page 19, Binding sites: 181 - 190; Page 20, Binding sites: 191 - 200; Page 21, Binding sites: 201 - 210; Page 22, Binding sites: 211 - 220; Page 23, Binding sites: 221 - 230;

Binding sites:

The binding sites of Magnesium atom in the 48S Late-Stage Initiation Complex with Non Methylated Mrna (pdb code 8p09). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 230 binding sites of Magnesium where determined in the 48S Late-Stage Initiation Complex with Non Methylated Mrna, PDB code: 8p09:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1901 b:47.6 occ:1.00 OP2 2:U1833 1.9 48.5 1.0 O Q:LEU151 3.0 62.5 1.0 P 2:U1833 3.3 48.5 1.0 O5' 2:U1833 4.0 48.5 1.0 OP1 2:U1833 4.1 48.5 1.0 C Q:LEU151 4.1 62.5 1.0 N3 2:A1829 4.3 48.6 1.0 OXT Q:LEU151 4.4 62.5 1.0 O3' 2:U1832 4.4 51.3 1.0 C2 2:A1829 4.5 48.6 1.0 C3' 2:U1832 4.7 51.3 1.0 N6 2:A1857 4.7 45.7 1.0 C4' 2:U1832 4.9 51.3 1.0 N3 3:C48 4.9 93.2 1.0 N1 2:A1857 4.9 45.7 1.0

Magnesium binding site 2 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1902 b:65.6 occ:1.00 O4 2:U1821 3.6 74.0 1.0 O6 2:G1820 4.2 81.6 1.0 O6 2:G1701 4.4 59.4 1.0 C4 2:U1821 4.7 74.0 1.0 O4 2:U1702 4.8 65.5 1.0

Magnesium binding site 3 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1903 b:63.9 occ:1.00 O4 2:U1824 3.7 58.5 1.0 O6 2:G1823 3.7 59.9 1.0 N4 2:C1822 4.1 64.5 1.0 MG 2:MG1906 4.3 69.2 1.0 N7 2:G1823 4.4 59.9 1.0 C6 2:G1823 4.6 59.9 1.0 C4 2:U1824 4.7 58.5 1.0 OP1 3:G54 4.8 72.2 1.0 C5 2:G1823 4.9 59.9 1.0 N4 2:C1700 4.9 56.3 1.0

Magnesium binding site 4 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1904 b:62.8 occ:1.00 OP1 2:C1698 3.1 56.5 1.0 OP2 2:C1698 3.5 56.5 1.0 P 2:C1698 3.7 56.5 1.0 O3' 2:G1697 4.3 55.5 1.0 O2 2:C1693 4.5 58.8 1.0

Magnesium binding site 5 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1905 b:50.4 occ:1.00 OP1 2:A1191 3.7 48.5 1.0 OP1 2:C612 4.3 48.9 1.0 OP2 2:G613 4.4 54.3 1.0 OP1 2:A1190 4.8 48.5 1.0

Magnesium binding site 6 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1906 b:69.2 occ:1.00 O2' 3:U53 4.2 69.3 1.0 MG 2:MG1903 4.3 63.9 1.0 O4 2:U1824 4.6 58.5 1.0 N7 2:G1823 5.0 59.9 1.0 OP2 2:C1822 5.0 64.5 1.0

Magnesium binding site 7 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1907 b:53.9 occ:1.00 OP1 2:U1834 2.0 47.3 1.0 OP1 2:G1831 2.1 51.7 1.0 OP1 2:A1826 2.7 50.8 1.0 P 2:U1834 3.1 47.3 1.0 O3' 2:U1833 3.2 48.5 1.0 P 2:G1831 3.6 51.7 1.0 O2' 2:U1832 3.7 51.3 1.0 OP1 2:G1830 4.0 49.6 1.0 OP2 2:U1834 4.1 47.3 1.0 P 2:A1826 4.1 50.8 1.0 O5' 2:U1834 4.2 47.3 1.0 C5' 2:U1834 4.2 47.3 1.0 C3' 2:G1830 4.3 49.6 1.0 C5' 2:G1831 4.4 51.7 1.0 O3' 2:G1830 4.5 49.6 1.0 C3' 2:U1833 4.5 48.5 1.0 OP2 2:G1831 4.5 51.7 1.0 O5' 2:G1831 4.5 51.7 1.0 C2' 2:U1832 4.6 51.3 1.0 OP2 2:A1826 4.7 50.8 1.0 OP2 2:C1827 4.8 49.3 1.0 C4' 2:U1833 4.8 48.5 1.0 O5' 2:A1826 5.0 50.8 1.0 P 2:G1830 5.0 49.6 1.0

Magnesium binding site 8 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1908 b:53.5 occ:1.00 OP2 2:A1825 1.8 52.7 1.0 OP2 2:A1826 2.8 50.8 1.0 P 2:A1825 2.9 52.7 1.0 O3' 2:U1824 3.0 58.5 1.0 O5' 2:A1825 3.4 52.7 1.0 O2' 2:U1824 3.5 58.5 1.0 OP2 2:G1831 3.6 51.7 1.0 N7 2:A1826 4.0 50.8 1.0 C3' 2:U1824 4.0 58.5 1.0 P 2:A1826 4.2 50.8 1.0 OP1 2:A1825 4.2 52.7 1.0 C2' 2:U1824 4.3 58.5 1.0 C5' 2:A1825 4.5 52.7 1.0 C3' 2:A1825 4.5 52.7 1.0 C8 2:A1826 4.6 50.8 1.0 O2' 2:G1830 4.6 49.6 1.0 O3' 2:G1830 4.6 49.6 1.0 P 2:G1831 4.6 51.7 1.0 C8 2:A1825 4.8 52.7 1.0 O3' 2:A1825 4.8 52.7 1.0 O5' 2:A1826 4.9 50.8 1.0 N7 2:A1825 4.9 52.7 1.0

Magnesium binding site 9 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1909 b:60.1 occ:1.00 MG 2:MG1910 1.1 58.6 1.0 OP2 2:A1195 3.9 46.7 1.0 N7 2:A1195 4.1 46.7 1.0 OP2 2:G1194 4.3 45.4 1.0 N6 2:A1196 4.7 47.8 1.0 C8 2:A1195 4.8 46.7 1.0 OP1 2:A1690 4.8 48.4 1.0

Magnesium binding site 10 out of 230 in the 48S Late-Stage Initiation Complex with Non Methylated Mrna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of 48S Late-Stage Initiation Complex with Non Methylated Mrna within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1910 b:58.6 occ:1.00 MG 2:MG1909 1.1 60.1 1.0 OP2 2:A1195 3.2 46.7 1.0 N7 2:A1195 3.3 46.7 1.0 C8 2:A1195 3.8 46.7 1.0 P 2:A1195 4.5 46.7 1.0 N6 2:A1196 4.5 47.8 1.0 O5' 2:A1195 4.5 46.7 1.0 C5 2:A1195 4.5 46.7 1.0 N7 2:A1196 4.6 47.8 1.0 OP2 2:G1194 4.9 45.4 1.0 C3' 2:G1194 5.0 45.4 1.0

E.Guca, R.Alarcon, M.Z.Palo, L.Santos, S.Alonso-Gil, M.Davyt, L.H.F.De Lima, F.Boissier, S.Das, B.Zagrovic, J.D.Puglisi, Y.Hashem, Z.Ignatova. N 6 -Methyladenosine in 5' Utr Does Not Promote Translation Initiation. Mol.Cell V. 84 584 2024.
ISSN: ISSN 1097-2765
PubMed: 38244546
DOI: 10.1016/J.MOLCEL.2023.12.028