Magnesium in PDB 8sbt: Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36

The structure of Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36, PDB code: 8sbt was solved by N.S.Que, D.T.Gewirth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.35 / 1.50
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	66.613, 90.664, 98.476, 90, 90, 90
R / Rfree (%)	17.3 / 19.7

The binding sites of Magnesium atom in the Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36 (pdb code 8sbt). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36, PDB code: 8sbt:

Magnesium binding site 1 out of 1 in the Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human HSP90-Alpha Bound to Purine Inhibitor Pu-H36 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:21.0 occ:1.00 O A:HOH464 3.0 38.7 1.0 N A:GLN23 3.1 18.9 1.0 O A:HOH467 3.3 21.1 1.0 CG A:GLN23 3.5 35.1 1.0 CA A:PHE22 3.7 18.3 1.0 CA A:GLY108 3.8 28.1 1.0 CD1 A:PHE22 3.8 16.1 1.0 CG1 A:ILE26 3.8 28.4 1.0 CB A:GLN23 3.9 24.8 1.0 C A:PHE22 3.9 19.5 1.0 O A:HOH511 4.0 45.9 1.0 CA A:GLN23 4.1 21.2 1.0 CB A:PHE22 4.1 18.1 1.0 CB A:ILE26 4.1 17.7 1.0 CG2 A:ILE26 4.4 16.8 1.0 CG A:PHE22 4.5 16.1 1.0 C A:GLY108 4.5 24.4 1.0 O A:HOH554 4.6 19.6 1.0 CE1 A:PHE170 4.7 16.9 1.0 N A:GLY108 4.8 22.6 1.0 CE1 A:PHE22 4.8 16.2 1.0 O A:GLY108 4.8 26.7 1.0 O A:HOH437 4.8 29.4 1.0 CD A:GLN23 4.9 52.5 1.0 O A:GLN23 4.9 22.3 1.0 O A:ALA21 4.9 19.8 1.0 N A:PHE22 5.0 18.2 1.0

N.S.Que, D.T.Gewirth. Selective Binding to GRP94 and HSP90 To Be Published.