Magnesium in PDB 8yi9: Human PRPS2 ISOFORM2

All present enzymatic activity of Human PRPS2 ISOFORM2:
2.7.6.1;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Magnesium atom in the Human PRPS2 ISOFORM2 (pdb code 8yi9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 12 binding sites of Magnesium where determined in the Human PRPS2 ISOFORM2, PDB code: 8yi9:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:25.9 occ:1.00 O2 A:RP5401 2.1 32.0 1.0 OD2 A:ASP174 2.3 42.2 1.0 C1 A:RP5401 2.6 36.6 1.0 C2 A:RP5401 2.8 35.1 1.0 CG A:ASP174 3.5 41.0 1.0 O1 A:RP5401 3.5 37.5 1.0 O4 A:RP5401 3.6 37.8 1.0 C3 A:RP5401 3.8 31.0 1.0 O1A F:ADP401 3.9 24.7 1.0 O3 A:RP5401 3.9 33.1 1.0 C4 A:RP5401 4.1 34.3 1.0 OD1 A:ASP174 4.2 40.1 1.0 OD2 A:ASP223 4.6 35.8 1.0 CB A:ASP174 4.6 35.6 1.0 O2A F:ADP401 4.6 36.6 1.0 O3B F:ADP401 4.6 30.8 1.0 OD1 A:ASP223 4.6 41.3 1.0 CE1 A:HIS133 4.7 22.8 1.0 PA F:ADP401 4.8 41.4 1.0 OD1 A:ASP224 4.8 31.9 1.0

Magnesium binding site 2 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:23.1 occ:1.00 O2A F:ADP401 2.1 36.6 1.0 NE2 A:HIS133 2.1 27.9 1.0 O3B F:ADP401 2.9 30.8 1.0 CE1 A:HIS133 3.0 22.8 1.0 CD2 A:HIS133 3.1 22.5 1.0 PA F:ADP401 3.3 41.4 1.0 O3A F:ADP401 3.5 32.5 1.0 PB F:ADP401 3.7 48.0 1.0 O2B F:ADP401 4.0 31.7 1.0 NZ A:LYS99 4.0 27.2 1.0 O1 A:RP5401 4.1 37.5 1.0 ND1 A:HIS133 4.2 19.7 1.0 CG A:HIS133 4.2 19.7 1.0 O1A F:ADP401 4.4 24.7 1.0 C5' F:ADP401 4.4 28.6 1.0 O5' F:ADP401 4.4 32.3 1.0 OD2 A:ASP98 4.5 24.3 1.0 OD1 A:ASP98 4.6 22.5 1.0 O A:ARG96 4.7 25.0 1.0 CG A:ARG96 5.0 20.6 1.0 CG A:ASP98 5.0 24.1 1.0

Magnesium binding site 3 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg402 b:27.2 occ:1.00 O2 B:RP5401 2.1 34.5 1.0 OD2 B:ASP174 2.2 45.0 1.0 C1 B:RP5401 2.7 38.7 1.0 C2 B:RP5401 2.9 36.7 1.0 CG B:ASP174 3.4 45.7 1.0 O1 B:RP5401 3.6 43.8 1.0 O4 B:RP5401 3.7 39.6 1.0 C3 B:RP5401 3.9 33.6 1.0 O1A E:ADP401 3.9 23.6 1.0 O3 B:RP5401 4.0 35.8 1.0 OD1 B:ASP174 4.1 46.9 1.0 C4 B:RP5401 4.1 37.4 1.0 CB B:ASP174 4.4 39.1 1.0 OD1 B:ASP223 4.5 36.1 1.0 O3B E:ADP401 4.7 30.6 1.0 CE1 B:HIS133 4.7 21.4 1.0 OD2 B:ASP223 4.8 43.5 1.0 O2A E:ADP401 4.8 33.2 1.0 PA E:ADP401 4.9 39.1 1.0 OD1 B:ASP224 4.9 35.5 1.0

Magnesium binding site 4 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg403 b:26.1 occ:1.00 O2A E:ADP401 2.0 33.2 1.0 NE2 B:HIS133 2.1 28.5 1.0 O3B E:ADP401 2.8 30.6 1.0 CE1 B:HIS133 3.1 21.4 1.0 CD2 B:HIS133 3.1 24.2 1.0 PA E:ADP401 3.3 39.1 1.0 O3A E:ADP401 3.7 33.0 1.0 PB E:ADP401 3.8 48.8 1.0 NZ B:LYS99 3.9 26.0 1.0 O2B E:ADP401 4.1 32.9 1.0 ND1 B:HIS133 4.2 19.5 1.0 O1 B:RP5401 4.2 43.8 1.0 CG B:HIS133 4.2 20.9 1.0 O1A E:ADP401 4.3 23.6 1.0 O5' E:ADP401 4.4 31.7 1.0 C5' E:ADP401 4.4 30.2 1.0 OD2 B:ASP98 4.6 21.6 1.0 OD1 B:ASP98 4.6 22.7 1.0 O B:ARG96 4.7 23.1 1.0

Magnesium binding site 5 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg402 b:31.9 occ:1.00 O2 C:RP5401 2.2 36.8 1.0 OD2 C:ASP174 2.2 46.0 1.0 C1 C:RP5401 2.6 39.8 1.0 C2 C:RP5401 2.9 39.2 1.0 CG C:ASP174 3.4 45.7 1.0 O1 C:RP5401 3.5 43.6 1.0 O4 C:RP5401 3.6 40.6 1.0 C3 C:RP5401 3.9 37.1 1.0 O3 C:RP5401 4.0 39.9 1.0 OD1 C:ASP174 4.1 46.2 1.0 C4 C:RP5401 4.1 40.8 1.0 O1A D:ADP401 4.1 30.7 1.0 OD2 C:ASP223 4.4 38.2 1.0 CB C:ASP174 4.5 40.2 1.0 OD1 C:ASP223 4.6 47.9 1.0 O3B D:ADP401 4.7 29.9 1.0 O2A D:ADP401 4.7 39.3 1.0 CE1 C:HIS133 4.8 21.3 1.0 OD1 C:ASP224 4.8 37.2 1.0 CG C:ASP223 4.9 41.8 1.0 PA D:ADP401 5.0 43.1 1.0

Magnesium binding site 6 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg403 b:29.4 occ:1.00 O2A D:ADP401 2.0 39.3 1.0 NE2 C:HIS133 2.1 27.1 1.0 O3B D:ADP401 3.0 29.9 1.0 CE1 C:HIS133 3.0 21.3 1.0 CD2 C:HIS133 3.2 22.6 1.0 PA D:ADP401 3.3 43.1 1.0 O3A D:ADP401 3.4 34.1 1.0 PB D:ADP401 3.7 45.4 1.0 NZ C:LYS99 4.0 27.4 1.0 O2B D:ADP401 4.0 34.7 1.0 O1 C:RP5401 4.1 43.6 1.0 ND1 C:HIS133 4.1 18.2 1.0 CG C:HIS133 4.2 19.1 1.0 O1A D:ADP401 4.3 30.7 1.0 O5' D:ADP401 4.3 31.9 1.0 C5' D:ADP401 4.4 32.2 1.0 OD1 C:ASP98 4.6 26.4 1.0 OD2 C:ASP98 4.6 20.5 1.0 O C:ARG96 4.7 23.4 1.0 CG C:ARG96 5.0 20.6 1.0

Magnesium binding site 7 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg403 b:25.8 occ:1.00 O2 D:RP5402 2.1 31.8 1.0 OD2 D:ASP174 2.3 42.8 1.0 C1 D:RP5402 2.6 36.1 1.0 C2 D:RP5402 2.8 34.1 1.0 CG D:ASP174 3.5 41.8 1.0 O1 D:RP5402 3.5 37.5 1.0 O4 D:RP5402 3.6 37.5 1.0 C3 D:RP5402 3.8 30.7 1.0 O2A C:ADP404 3.9 24.1 1.0 O3 D:RP5402 3.9 33.2 1.0 C4 D:RP5402 4.1 33.8 1.0 OD1 D:ASP174 4.2 41.2 1.0 OD2 D:ASP223 4.6 35.6 1.0 CB D:ASP174 4.6 36.3 1.0 O1A C:ADP404 4.6 36.0 1.0 O1B C:ADP404 4.6 30.3 1.0 OD1 D:ASP223 4.6 41.6 1.0 CE1 D:HIS133 4.7 22.3 1.0 PA C:ADP404 4.8 40.5 1.0 OD1 D:ASP224 4.8 32.4 1.0

Magnesium binding site 8 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg404 b:24.4 occ:1.00 O1A C:ADP404 2.1 36.0 1.0 NE2 D:HIS133 2.1 28.1 1.0 O1B C:ADP404 2.9 30.3 1.0 CE1 D:HIS133 3.0 22.3 1.0 CD2 D:HIS133 3.1 22.4 1.0 PA C:ADP404 3.3 40.5 1.0 O3A C:ADP404 3.5 32.0 1.0 PB C:ADP404 3.7 47.0 1.0 O2B C:ADP404 4.0 30.9 1.0 NZ D:LYS99 4.0 26.8 1.0 O1 D:RP5402 4.1 37.5 1.0 ND1 D:HIS133 4.1 20.0 1.0 CG D:HIS133 4.2 19.5 1.0 O2A C:ADP404 4.4 24.1 1.0 C5' C:ADP404 4.4 28.3 1.0 O5' C:ADP404 4.4 32.0 1.0 OD2 D:ASP98 4.5 24.3 1.0 OD1 D:ASP98 4.6 22.0 1.0 O D:ARG96 4.7 24.4 1.0 CG D:ARG96 5.0 20.4 1.0

Magnesium binding site 9 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg403 b:27.0 occ:1.00 O2 E:RP5402 2.1 34.8 1.0 OD2 E:ASP174 2.2 46.5 1.0 C1 E:RP5402 2.7 39.9 1.0 C2 E:RP5402 2.9 37.2 1.0 CG E:ASP174 3.4 47.0 1.0 O1 E:RP5402 3.6 44.8 1.0 O4 E:RP5402 3.7 41.0 1.0 C3 E:RP5402 3.9 33.7 1.0 O2A B:ADP404 3.9 24.9 1.0 O3 E:RP5402 4.0 36.5 1.0 OD1 E:ASP174 4.1 47.2 1.0 C4 E:RP5402 4.1 37.9 1.0 CB E:ASP174 4.4 40.3 1.0 OD1 E:ASP223 4.5 36.8 1.0 O1B B:ADP404 4.7 30.8 1.0 CE1 E:HIS133 4.7 22.0 1.0 OD2 E:ASP223 4.8 44.2 1.0 O1A B:ADP404 4.8 33.1 1.0 PA B:ADP404 4.9 39.8 1.0 OD1 E:ASP224 4.9 36.6 1.0

Magnesium binding site 10 out of 12 in the Human PRPS2 ISOFORM2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Human PRPS2 ISOFORM2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg404 b:26.8 occ:1.00 O1A B:ADP404 2.0 33.1 1.0 NE2 E:HIS133 2.1 28.8 1.0 O1B B:ADP404 2.8 30.8 1.0 CE1 E:HIS133 3.1 22.0 1.0 CD2 E:HIS133 3.1 24.0 1.0 PA B:ADP404 3.3 39.8 1.0 O3A B:ADP404 3.7 33.4 1.0 PB B:ADP404 3.8 48.9 1.0 NZ E:LYS99 3.9 26.4 1.0 O2B B:ADP404 4.1 33.1 1.0 ND1 E:HIS133 4.2 20.2 1.0 O1 E:RP5402 4.2 44.8 1.0 CG E:HIS133 4.2 21.0 1.0 O2A B:ADP404 4.3 24.9 1.0 O5' B:ADP404 4.4 32.0 1.0 C5' B:ADP404 4.4 30.4 1.0 OD2 E:ASP98 4.6 21.7 1.0 OD1 E:ASP98 4.6 24.3 1.0 O E:ARG96 4.7 22.8 1.0

J.L.Liu, G.M.Lu. Structure of Human PRPS2 Long Isoform at 3.4 Angstroms Resolution. To Be Published.