Magnesium in PDB 9ctg: Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas

All present enzymatic activity of Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas:
7.6.2.1; 7.6.2.2;

The binding sites of Magnesium atom in the Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas (pdb code 9ctg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas, PDB code: 9ctg:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1310 b:18.7 occ:1.00 O1B A:AGS1312 1.9 74.8 1.0 O3B A:AGS1312 2.2 62.4 1.0 PB A:AGS1312 2.5 75.8 1.0 O2G A:AGS1312 3.0 76.3 1.0 PG A:AGS1312 3.1 88.8 1.0 NE2 A:GLN1118 3.5 64.6 1.0 O2B A:AGS1312 3.6 66.8 1.0 O3A A:AGS1312 3.8 76.7 1.0 O3G A:AGS1312 3.9 87.7 1.0 NZ A:LYS1076 4.2 64.8 1.0 OG A:SER1072 4.2 80.1 1.0 N A:GLY533 4.3 55.0 1.0 OE1 A:GLN1118 4.3 58.8 1.0 CD A:GLN1118 4.4 63.1 1.0 N A:GLY1073 4.4 68.2 1.0 CA A:GLY533 4.6 55.7 1.0 N A:GLY534 4.6 55.7 1.0 CA A:SER1072 4.6 82.3 1.0 S1G A:AGS1312 4.8 78.3 1.0 CB A:SER1072 4.8 81.7 1.0 CE A:LYS1076 4.9 59.9 1.0 C A:GLY533 5.0 55.7 1.0 CB A:SER532 5.0 58.8 1.0

Magnesium binding site 2 out of 2 in the Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Sapnp Reconstituted Human ABCB1 Bound to Atp Gammas within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1311 b:43.8 occ:1.00 O2G A:AGS1313 2.0 60.8 1.0 O2B A:AGS1313 2.1 62.1 1.0 OE1 A:GLN475 2.1 61.2 1.0 OG A:SER434 2.1 55.2 1.0 CB A:SER434 3.2 54.9 1.0 CD A:GLN475 3.2 60.5 1.0 PG A:AGS1313 3.4 66.6 1.0 PB A:AGS1313 3.4 61.3 1.0 O3B A:AGS1313 3.8 59.3 1.0 O2A A:AGS1313 3.8 60.5 1.0 OD1 A:ASP555 3.8 85.8 1.0 NE2 A:GLN475 3.8 59.6 1.0 OD2 A:ASP555 3.9 77.5 1.0 O1B A:AGS1313 4.2 55.9 1.0 CG A:ASP555 4.2 80.9 1.0 O3G A:AGS1313 4.2 62.4 1.0 N A:SER434 4.3 55.0 1.0 CA A:SER434 4.3 50.7 1.0 CG A:GLN475 4.4 58.7 1.0 CB A:GLN475 4.5 62.1 1.0 O3A A:AGS1313 4.6 59.2 1.0 PA A:AGS1313 4.7 61.0 1.0 S1G A:AGS1313 4.7 72.6 1.0 N A:GLY1178 5.0 49.9 1.0

D.Kurre, P.X.Dang, L.T.M.Le, V.V.Gadkari, A.Alam. Structural Insights Into Binding-Site Access and Ligand Recognition By Human ABCB1. Embo J. 2025.
ISSN: ESSN 1460-2075
PubMed: 39806099
DOI: 10.1038/S44318-025-00361-Z