Magnesium in PDB 9iyp: Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State

The binding sites of Magnesium atom in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State (pdb code 9iyp). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 7 binding sites of Magnesium where determined in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State, PDB code: 9iyp:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7;

Magnesium binding site 1 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg902 b:79.8 occ:1.00 OD1 B:ASP136 3.1 83.1 1.0 CG B:ASP136 3.9 83.1 1.0 OD2 B:ASP136 4.0 83.7 1.0 OD2 B:ASP181 4.2 58.1 1.0 CB B:ALA135 4.5 70.6 1.0 MG B:MG903 4.7 81.6 1.0 N B:ASP136 5.0 74.1 1.0

Magnesium binding site 2 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg903 b:81.6 occ:1.00 OD2 B:ASP354 2.8 85.3 1.0 CG B:ASP354 3.3 81.5 1.0 OD1 B:ASP354 3.4 82.6 1.0 CB B:ASP354 4.4 75.8 1.0 NH2 A:ARG174 4.6 73.1 1.0 MG B:MG902 4.7 79.8 1.0 CA B:ASP354 5.0 71.7 1.0

Magnesium binding site 3 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg904 b:58.4 occ:1.00 NE2 B:HIS127 3.3 75.6 1.0 CE1 B:HIS127 3.8 73.0 1.0 CD2 B:HIS127 4.1 76.5 1.0 CB B:LEU289 4.6 95.9 1.0 N B:LEU289 4.7 94.5 1.0 ND1 B:HIS127 4.8 71.8 1.0 CG B:HIS127 5.0 73.4 1.0

Magnesium binding site 4 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg905 b:30.0 occ:1.00 OE1 B:GLU191 3.1 75.8 1.0 CB B:GLU191 3.3 58.3 1.0 CD B:GLU191 3.5 74.2 1.0 O B:ARG187 3.7 40.2 1.0 CG B:GLU191 3.7 68.0 1.0 OE2 B:GLU191 4.2 71.0 1.0 CG2 B:ILE190 4.2 50.7 1.0 CA B:GLU191 4.3 56.5 1.0 N B:GLU191 4.4 60.0 1.0 C B:ARG187 4.4 39.8 1.0 CB B:ARG187 4.5 36.5 1.0 CA B:ARG187 4.7 36.4 1.0

Magnesium binding site 5 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg904 b:109.4 occ:1.00 OD1 C:ASN616 1.9 88.1 1.0 OD1 D:ASN615 2.5 97.8 1.0 OD1 B:ASN616 2.7 95.1 1.0 CG C:ASN616 2.9 91.2 1.0 O D:ASN615 3.2 94.2 1.0 ND2 C:ASN616 3.2 94.9 1.0 CG B:ASN616 3.6 94.0 1.0 CG D:ASN615 3.7 95.1 1.0 ND2 B:ASN616 3.9 92.7 1.0 O B:ASN615 3.9 83.9 1.0 CB C:ASN616 4.2 89.4 1.0 OD1 B:ASN615 4.2 76.5 1.0 C D:ASN615 4.4 91.4 1.0 O D:ASN616 4.5 94.3 1.0 ND2 D:ASN615 4.6 95.8 1.0 ND2 A:ASN616 4.6 87.1 1.0 CB D:ASN615 4.7 89.6 1.0 C B:ASN615 4.8 82.9 1.0 C D:ASN616 4.9 97.1 1.0 OD1 A:ASN616 5.0 86.8 1.0

Magnesium binding site 6 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg902 b:89.4 occ:1.00 NE2 D:HIS127 3.0 66.1 1.0 CE1 D:HIS127 3.5 62.8 1.0 CD2 D:HIS127 4.2 65.9 1.0 ND1 D:HIS127 4.7 66.2 1.0 CB D:GLU284 4.8 87.1 1.0 O D:GLU284 4.8 91.1 1.0 OE1 D:GLU284 4.9 94.4 1.0 CD D:GLU284 5.0 93.8 1.0

Magnesium binding site 7 out of 7 in the Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Structure of the Human GLUN1-N2B Nmda Receptors in the MG2+ Bound State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg903 b:60.3 occ:1.00 OD2 D:ASP181 3.7 59.6 1.0 OD1 D:ASP136 4.0 68.0 1.0 OD1 D:ASP181 4.1 58.9 1.0 CG D:ASP181 4.3 55.6 1.0 NH2 C:ARG174 4.6 66.0 1.0 OD2 D:ASP136 4.6 71.5 1.0 CG D:ASP136 4.7 69.3 1.0

X.Huang, X.Sun, Q.Wang, J.Zhang, H.Wen, W.J.Chen, S.Zhu. Structural Insights Into the Diverse Actions of Magnesium on Nmda Receptors Neuron 2025.
ISSN: ISSN 0896-6273
DOI: 10.1016/J.NEURON.2025.01.021