Magnesium in PDB 9iz2: Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don

All present enzymatic activity of Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don:
6.3.4.2;

The binding sites of Magnesium atom in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don (pdb code 9iz2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don, PDB code: 9iz2:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:25.4 occ:1.00 O2A A:DGT606 2.1 39.6 1.0 O1G A:DGT606 2.3 44.3 1.0 O1B A:DGT606 2.9 35.3 1.0 PA A:DGT606 3.5 34.3 1.0 PG A:DGT606 3.7 47.4 1.0 N2 A:DGT606 3.7 36.3 1.0 PB A:DGT606 3.9 34.9 1.0 O3A A:DGT606 4.1 29.2 1.0 O3B A:DGT606 4.2 39.0 1.0 O3G A:DGT606 4.3 35.2 1.0 O1A A:DGT606 4.3 32.2 1.0 O5' A:DGT606 4.5 37.3 1.0 C5' A:DGT606 4.6 32.9 1.0 O2G A:DGT606 4.7 38.2 1.0 C2 A:DGT606 4.9 37.1 1.0

Magnesium binding site 2 out of 4 in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg603 b:11.1 occ:1.00 OD2 A:ASP70 2.0 33.5 1.0 O33 A:5ZL607 2.1 23.7 1.0 O3B A:DAT605 2.1 27.6 1.0 OE2 A:GLU145 2.2 21.3 1.0 OD1 A:ASP70 2.3 40.3 1.0 CG A:ASP70 2.3 33.0 1.0 CD A:GLU145 3.2 17.7 1.0 PB A:DAT605 3.4 5.4 1.0 O2A A:DAT605 3.5 26.4 1.0 OE1 A:GLU145 3.5 26.1 1.0 P30 A:5ZL607 3.6 22.8 1.0 N A:GLY17 3.6 19.7 1.0 O2B A:DAT605 3.7 27.6 1.0 CA A:GLY17 3.7 17.2 1.0 CB A:ASP70 3.7 20.3 1.0 NZ A:LYS38 4.0 13.0 1.0 O32 A:5ZL607 4.2 26.4 1.0 MG A:MG604 4.2 7.3 1.0 CE A:LYS38 4.3 8.1 1.0 O3A A:DAT605 4.3 12.3 1.0 O12 A:5ZL607 4.4 13.0 1.0 O1B A:DAT605 4.4 7.6 1.0 O31 A:5ZL607 4.5 17.8 1.0 PA A:DAT605 4.5 23.8 1.0 CG A:GLU145 4.6 8.3 1.0 C A:LYS16 4.6 7.2 1.0 CD A:LYS38 4.7 14.2 1.0 CA A:ASP70 4.8 24.4 1.0 CB A:LYS16 4.8 12.4 1.0 CE A:LYS16 5.0 0.5 1.0

Magnesium binding site 3 out of 4 in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg604 b:7.3 occ:1.00 O32 A:5ZL607 2.1 26.4 1.0 O2B A:DAT605 2.5 27.6 1.0 P30 A:5ZL607 3.3 22.8 1.0 O33 A:5ZL607 3.5 23.7 1.0 O A:SER12 3.8 31.8 1.0 PB A:DAT605 3.8 5.4 1.0 O12 A:5ZL607 4.1 13.0 1.0 MG A:MG603 4.2 11.1 1.0 O3B A:DAT605 4.2 27.6 1.0 O A:HIS55 4.3 29.4 1.0 O2A A:DAT605 4.3 26.4 1.0 O31 A:5ZL607 4.4 17.8 1.0 OD2 A:ASP68 4.5 36.6 1.0 OD2 A:ASP70 4.7 33.5 1.0 O3A A:DAT605 4.7 12.3 1.0 O5' A:DAT605 4.7 23.3 1.0 OD1 A:ASP70 4.8 40.3 1.0 O1B A:DAT605 4.8 7.6 1.0 C28 A:5ZL607 4.8 10.2 1.0 C A:SER12 4.9 20.4 1.0 C29 A:5ZL607 4.9 19.3 1.0 PA A:DAT605 4.9 23.8 1.0 CB A:HIS55 5.0 22.1 1.0

Magnesium binding site 4 out of 4 in the Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Focus Refinement Dmctps Bound with Datp Dutp Dgtp and Don within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg601 b:28.1 occ:1.00 O15 A:5ZL607 2.4 28.0 1.0 O11 A:5ZL607 2.5 6.4 1.0 O17 A:5ZL607 2.8 28.5 1.0 P02 A:5ZL607 3.7 10.5 1.0 O A:GLU54 3.7 25.0 1.0 NZ B:LYS228 3.7 24.8 1.0 P01 A:5ZL607 3.8 2.2 1.0 P03 A:5ZL607 4.0 16.1 1.0 O09 A:5ZL607 4.2 9.3 1.0 O13 A:5ZL607 4.3 19.3 1.0 O16 A:5ZL607 4.3 19.3 1.0 O07 A:5ZL607 4.5 18.2 1.0 NZ B:LYS192 4.7 12.9 1.0 O14 A:5ZL607 4.8 28.4 1.0 C A:GLU54 4.9 28.4 1.0 OE2 B:GLU190 4.9 34.8 1.0 O10 A:5ZL607 4.9 15.6 1.0 OE1 B:GLU190 5.0 34.7 1.0

C.J.Guo, Z.Zhang, J.L.Lu, J.Zhong, Y.F.Wu, S.Y.Guo, J.L.Liu. Structural Basis of Bifunctional Ctp/Dctp Synthase. J.Mol.Biol. V. 436 68750 2024.
ISSN: ESSN 1089-8638
PubMed: 39173734
DOI: 10.1016/J.JMB.2024.168750