Atomistry » Magnesium » PDB 1mf0-1muh » 1mq4
Atomistry »
  Magnesium »
    PDB 1mf0-1muh »
      1mq4 »

Magnesium in PDB 1mq4: Crystal Structure of Aurora-A Protein Kinase

Protein crystallography data

The structure of Crystal Structure of Aurora-A Protein Kinase, PDB code: 1mq4 was solved by J.Nowakowski, C.N.Cronin, D.E.Mcree, M.W.Knuth, C.Nelson, N.P.Pavletich, J.Rodgers, B.-C.Sang, D.N.Scheibe, R.V.Swanson, D.A.Thompson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 40.00 / 1.90
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 80.452, 80.452, 172.172, 90.00, 90.00, 120.00
R / Rfree (%) 22.5 / 27.3

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Aurora-A Protein Kinase (pdb code 1mq4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Aurora-A Protein Kinase, PDB code: 1mq4:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 1mq4

Go back to Magnesium Binding Sites List in 1mq4
Magnesium binding site 1 out of 2 in the Crystal Structure of Aurora-A Protein Kinase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Aurora-A Protein Kinase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg2086

b:29.9
occ:1.00
O1B A:ADP2001 1.9 30.3 1.0
O A:HOH3003 2.0 29.6 1.0
O A:HOH2098 2.0 38.0 1.0
OD2 A:ASP274 2.1 32.6 1.0
O A:HOH3022 2.1 39.3 1.0
O A:HOH3004 2.4 44.0 1.0
OD1 A:ASP274 2.6 29.4 1.0
CG A:ASP274 2.7 31.8 1.0
PB A:ADP2001 3.2 32.9 1.0
O3B A:ADP2001 3.6 30.6 1.0
O A:HOH2097 3.7 41.8 1.0
O A:HOH3013 3.9 32.3 1.0
NZ A:LYS162 3.9 33.1 1.0
MG A:MG2088 4.1 29.4 1.0
O2B A:ADP2001 4.1 35.7 1.0
CB A:ASP274 4.2 30.9 1.0
O A:HOH3070 4.3 32.0 1.0
O3A A:ADP2001 4.3 32.4 1.0
OE2 A:GLU181 4.3 46.4 1.0
CA A:GLY276 4.6 35.0 1.0
N A:GLY276 4.7 34.4 1.0
O2A A:ADP2001 4.7 29.3 1.0
CA A:ASP274 4.8 31.6 1.0
PA A:ADP2001 4.9 31.6 1.0
O A:ASP274 4.9 31.0 1.0
C A:ASP274 4.9 31.4 1.0
OD2 A:ASP256 5.0 36.7 1.0

Magnesium binding site 2 out of 2 in 1mq4

Go back to Magnesium Binding Sites List in 1mq4
Magnesium binding site 2 out of 2 in the Crystal Structure of Aurora-A Protein Kinase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Aurora-A Protein Kinase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg2088

b:29.4
occ:1.00
O2A A:ADP2001 1.9 29.3 1.0
OD1 A:ASP274 1.9 29.4 1.0
O3B A:ADP2001 2.0 30.6 1.0
O A:HOH3070 2.0 32.0 1.0
OD1 A:ASN261 2.0 29.8 1.0
O A:HOH3009 2.0 35.8 1.0
CG A:ASP274 3.0 31.8 1.0
CG A:ASN261 3.1 28.6 1.0
PB A:ADP2001 3.1 32.9 1.0
PA A:ADP2001 3.2 31.6 1.0
CB A:ASP274 3.5 30.9 1.0
O3A A:ADP2001 3.5 32.4 1.0
O1B A:ADP2001 3.5 30.3 1.0
ND2 A:ASN261 3.6 26.2 1.0
O A:HOH3003 3.7 29.6 1.0
OD2 A:ASP274 4.0 32.6 1.0
O A:HOH3021 4.0 41.1 1.0
MG A:MG2086 4.1 29.9 1.0
O1A A:ADP2001 4.1 30.5 1.0
O5' A:ADP2001 4.2 31.8 1.0
O A:HOH3001 4.2 32.9 1.0
CB A:ASN261 4.4 29.2 1.0
C5' A:ADP2001 4.4 32.0 1.0
O2B A:ADP2001 4.4 35.7 1.0
O A:GLU260 4.6 31.4 1.0
O3' A:ADP2001 4.7 33.2 1.0
CA A:ASN261 4.7 29.5 1.0
OD2 A:ASP256 4.9 36.7 1.0
C A:GLU260 4.9 30.4 1.0
CA A:ASP274 5.0 31.6 1.0

Reference:

J.Nowakowski, C.N.Cronin, D.E.Mcree, M.W.Knuth, C.Nelson, N.P.Pavletich, J.Rodgers, B.-C.Sang, D.N.Scheibe, R.V.Swanson, D.A.Thompson. Structures of the Cancer-Related Aurora-A, Fak and EPHA2 Protein Kinases From Nanovolume Crystallography Structure V. 10 1659 2002.
ISSN: ISSN 0969-2126
PubMed: 12467573
DOI: 10.1016/S0969-2126(02)00907-3
Page generated: Mon Dec 14 06:29:31 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy