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Atomistry » Magnesium » PDB 1so6-1t5s » 1t5a | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 1so6-1t5s » 1t5a » |
Magnesium in PDB 1t5a: Human Pyruvate Kinase M2Enzymatic activity of Human Pyruvate Kinase M2
All present enzymatic activity of Human Pyruvate Kinase M2:
2.7.1.40; Protein crystallography data
The structure of Human Pyruvate Kinase M2, PDB code: 1t5a
was solved by
J.D.Dombrauckas,
B.D.Santarsiero,
A.D.Mesecar,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1t5a:
The structure of Human Pyruvate Kinase M2 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human Pyruvate Kinase M2
(pdb code 1t5a). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Human Pyruvate Kinase M2, PDB code: 1t5a: Jump to Magnesium binding site number: 1; 2; 3; 4; Magnesium binding site 1 out of 4 in 1t5aGo back to Magnesium Binding Sites List in 1t5a
Magnesium binding site 1 out
of 4 in the Human Pyruvate Kinase M2
Mono view Stereo pair view
Magnesium binding site 2 out of 4 in 1t5aGo back to Magnesium Binding Sites List in 1t5a
Magnesium binding site 2 out
of 4 in the Human Pyruvate Kinase M2
Mono view Stereo pair view
Magnesium binding site 3 out of 4 in 1t5aGo back to Magnesium Binding Sites List in 1t5a
Magnesium binding site 3 out
of 4 in the Human Pyruvate Kinase M2
Mono view Stereo pair view
Magnesium binding site 4 out of 4 in 1t5aGo back to Magnesium Binding Sites List in 1t5a
Magnesium binding site 4 out
of 4 in the Human Pyruvate Kinase M2
Mono view Stereo pair view
Reference:
J.D.Dombrauckas,
B.D.Santarsiero,
A.D.Mesecar.
Structural Basis For Tumor Pyruvate Kinase M2 Allosteric Regulation and Catalysis. Biochemistry V. 44 9417 2005.
Page generated: Tue Aug 13 14:26:23 2024
ISSN: ISSN 0006-2960 PubMed: 15996096 DOI: 10.1021/BI0474923 |
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