Magnesium in PDB 2ad5: Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution.

Enzymatic activity of Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution.

All present enzymatic activity of Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution.:
6.3.4.2;

Protein crystallography data

The structure of Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution., PDB code: 2ad5 was solved by J.A.Endrizzi, H.Kim, P.M.Anderson, E.P.Baldwin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	20.00 / 2.80
*Space group*	P 2₁ 2₁ 2
*Cell size a, b, c (Å), α, β, γ (°)*	163.270, 106.380, 130.470, 90.00, 90.00, 90.00
*R / R_free (%)*	n/a / n/a

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution. (pdb code 2ad5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution., PDB code: 2ad5:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2ad5

Go back to

Magnesium Binding Sites List in 2ad5

Magnesium binding site 1 out of 2 in the Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution.

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution. within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mg701 b:32.8 occ:1.00	OE2	A:GLU140	2.1	52.3	1.0
	O1B	A:ADP601	2.1	50.4	1.0
	OD2	A:ASP72	2.3	70.5	1.0
	CD	A:GLU140	3.0	59.9	1.0
	OE1	A:GLU140	3.3	57.9	1.0
	CG	A:ASP72	3.3	62.6	1.0
	NZ	A:LYS40	3.4	76.5	1.0
	N	A:GLY19	3.4	43.2	1.0
	PB	A:ADP601	3.5	57.1	1.0
	OD1	A:ASP72	3.6	67.2	1.0
	CA	A:GLY19	3.7	43.4	1.0
	CE	A:LYS40	3.8	47.3	1.0
	O2A	A:ADP601	3.8	0.0	1.0
	O	A:HOH784	3.8	74.8	1.0
	O2B	A:ADP601	4.1	42.2	1.0
	CB	A:LYS18	4.2	40.4	1.0
	O3B	A:ADP601	4.3	56.3	1.0
	CG	A:GLU140	4.3	41.2	1.0
	CE	A:LYS18	4.4	40.1	1.0
	C	A:LYS18	4.5	44.6	1.0
	O3A	A:ADP601	4.5	89.1	1.0
	CD	A:LYS40	4.5	39.1	1.0
	PA	A:ADP601	4.6	98.9	1.0
	CB	A:ASP72	4.6	44.3	1.0
	NZ	A:LYS18	4.7	56.8	1.0
	O	A:HOH721	4.8	83.1	1.0
	CA	A:LYS18	4.8	39.7	1.0
	N	A:LYS18	4.8	41.1	1.0
	O1A	A:ADP601	4.9	78.0	1.0
	CG	A:LYS18	4.9	35.6	1.0

Magnesium binding site 2 out of 2 in 2ad5

Go back to

Magnesium Binding Sites List in 2ad5

Magnesium binding site 2 out of 2 in the Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution.

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Mechanisms of Feedback Regulation and Drug Resistance of Ctp Synthetases: Structure of the E. Coli Ctps/Ctp Complex at 2.8- Angstrom Resolution. within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
B:Mg1701 b:45.7 occ:1.00	OE2	B:GLU140	1.9	53.1	1.0
	O1B	B:ADP1601	2.0	61.1	1.0
	OD2	B:ASP72	2.2	63.8	1.0
	CD	B:GLU140	2.9	57.0	1.0
	CG	B:ASP72	3.2	59.6	1.0
	OE1	B:GLU140	3.2	59.2	1.0
	N	B:GLY19	3.4	43.3	1.0
	PB	B:ADP1601	3.5	60.1	1.0
	OD1	B:ASP72	3.6	68.1	1.0
	CA	B:GLY19	3.6	43.2	1.0
	O	B:HOH1741	3.8	58.0	1.0
	CE	B:LYS40	3.8	43.5	1.0
	CG	B:LYS18	4.1	48.2	1.0
	O2A	B:ADP1601	4.1	0.0	1.0
	O3B	B:ADP1601	4.2	48.3	1.0
	CG	B:GLU140	4.2	42.8	1.0
	NZ	B:LYS40	4.2	48.3	1.0
	O2B	B:ADP1601	4.2	48.4	1.0
	C	B:LYS18	4.3	46.8	1.0
	O3A	B:ADP1601	4.4	78.8	1.0
	CB	B:ASP72	4.4	40.0	1.0
	O1A	B:ADP1601	4.5	83.4	1.0
	PA	B:ADP1601	4.5	91.8	1.0
	CD	B:LYS40	4.6	42.2	1.0
	NZ	B:LYS18	4.7	60.8	1.0
	CE	B:LYS18	4.7	49.0	1.0
	CA	B:LYS18	4.8	44.3	1.0
	CB	B:LYS18	4.8	46.7	1.0
	N	B:LYS18	4.9	44.4	1.0
	CD	B:LYS18	5.0	42.6	1.0

Reference:

J.A.Endrizzi, H.Kim, P.M.Anderson, E.P.Baldwin. Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases From the Structure of A Ctp-Inhibited Complex(,). Biochemistry V. 44 13491 2005.
ISSN: ISSN 0006-2960
PubMed: 16216072
DOI: 10.1021/BI051282O

Page generated: Tue Aug 13 21:28:00 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy