Atomistry » Magnesium » PDB 2bt6-2c3y » 2c16
Atomistry »
  Magnesium »
    PDB 2bt6-2c3y »
      2c16 »

Magnesium in PDB 2c16: 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa

Enzymatic activity of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa

All present enzymatic activity of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa:
4.2.1.24;

Protein crystallography data

The structure of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa, PDB code: 2c16 was solved by F.Frere, M.Nentwich, S.Gacond, D.W.Heinz, R.Neier, N.Frankenberg-Dinkel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 89.80 / 2.02
Space group P 4 21 2
Cell size a, b, c (Å), α, β, γ (°) 125.513, 125.513, 86.765, 90.00, 90.00, 90.00
R / Rfree (%) 14.3 / 18.3

Other elements in 2c16:

The structure of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa (pdb code 2c16). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa, PDB code: 2c16:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2c16

Go back to Magnesium Binding Sites List in 2c16
Magnesium binding site 1 out of 2 in the 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1336

b:11.0
occ:1.00
 OE1 A:GLU245 2.0 9.2 1.0
O A:HOH2280 2.0 12.2 1.0
O A:HOH2234 2.1 7.8 1.0
O A:HOH2277 2.1 6.2 1.0
O A:HOH2279 2.1 9.2 1.0
O A:HOH2236 2.2 8.5 1.0
CD A:GLU245 3.1 11.0 1.0
OE2 A:GLU245 3.4 8.9 1.0
NH1 A:ARG181 3.8 10.3 1.0
OD1 A:ASP249 3.8 10.9 1.0
O A:HOH2233 4.0 9.1 1.0
O A:HOH2284 4.1 10.7 1.0
O A:HOH2283 4.2 8.2 1.0
OD2 A:ASP249 4.3 11.3 1.0
O A:MET178 4.3 8.5 1.0
CG A:GLU245 4.4 8.9 1.0
CG A:ASP249 4.4 9.7 1.0
OD1 A:ASP179 4.5 9.3 1.0
O A:SER203 4.5 8.7 1.0
O A:GLU245 4.5 8.2 1.0
O B:HOH2031 4.6 11.9 1.0
CB A:GLU245 4.6 9.7 1.0
CA A:ASP179 4.7 8.6 1.0
CA A:GLU245 4.7 9.3 1.0
SD A:MET177 4.9 11.3 1.0
C A:MET178 5.0 8.8 1.0

Magnesium binding site 2 out of 2 in 2c16

Go back to Magnesium Binding Sites List in 2c16
Magnesium binding site 2 out of 2 in the 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of 5-(4-Carboxy-2-Oxo-Butane-1-Sulfinyl)-4-Oxo-Pentanoic Acid Acid Bound to Porphobilinogen Synthase From Pseudomonas Aeruginosa within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg1336

b:14.8
occ:1.00
 OE1 B:GLU245 2.0 15.8 1.0
O B:HOH2267 2.1 15.8 1.0
O B:HOH2264 2.1 11.1 1.0
O B:HOH2225 2.1 9.3 1.0
O B:HOH2266 2.1 10.8 1.0
O B:HOH2226 2.3 11.6 1.0
CD B:GLU245 3.1 14.2 1.0
OE2 B:GLU245 3.5 14.0 1.0
NH1 B:ARG181 3.7 12.6 1.0
OD1 B:ASP249 3.8 11.7 1.0
O B:HOH2224 4.1 10.6 1.0
O B:HOH2270 4.1 11.1 1.0
OD2 B:ASP249 4.2 11.5 1.0
O B:HOH2271 4.2 14.6 1.0
O B:MET178 4.3 10.6 1.0
CG B:ASP249 4.4 10.9 1.0
CG B:GLU245 4.4 12.4 1.0
O B:SER203 4.5 9.5 1.0
O B:GLU245 4.6 9.7 1.0
OD1 B:ASP179 4.6 10.0 1.0
CB B:GLU245 4.6 11.0 1.0
CA B:ASP179 4.7 11.7 1.0
CA B:GLU245 4.7 10.5 1.0
O A:HOH2028 4.8 14.7 1.0
SD B:MET177 4.9 12.6 1.0
CZ B:ARG181 5.0 12.8 1.0
CE B:MET177 5.0 9.6 1.0

Reference:

F.Frere, M.Nentwich, S.Gacond, D.W.Heinz, R.Neier, N.Frankenberg-Dinkel. Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry V. 45 8243 2006.
ISSN: ISSN 0006-2960
PubMed: 16819823
DOI: 10.1021/BI052611F
Page generated: Tue Aug 13 22:07:47 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy