Magnesium in PDB 2iyf: The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering

The structure of The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering, PDB code: 2iyf was solved by D.N.Bolam, S.M.Roberts, M.R.Proctor, J.P.Turkenburg, E.J.Dodson, C.Martinez-Fleites, M.Yang, B.G.Davis, G.J.Davies, H.J.Gilbert, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.88 / 1.7
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	72.718, 65.778, 91.940, 90.00, 100.42, 90.00
R / Rfree (%)	20 / 23.2

The binding sites of Magnesium atom in the The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering (pdb code 2iyf). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering, PDB code: 2iyf:

Magnesium binding site 1 out of 1 in the The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The Crystal Structure of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1401 b:23.8 occ:1.00 O B:HOH2215 2.1 20.8 1.0 O B:HOH2212 2.1 19.8 1.0 O B:THR317 2.2 13.5 1.0 O B:HOH2213 2.3 29.7 1.0 O B:HOH2216 2.4 21.6 1.0 C B:THR317 3.4 12.6 1.0 O B:ALA318 4.0 12.3 1.0 O B:HOH2206 4.2 34.6 1.0 C B:ALA318 4.2 12.3 1.0 O B:HOH2207 4.2 37.1 1.0 CB B:ALA318 4.2 11.7 1.0 OG1 B:THR319 4.2 12.4 1.0 CA B:THR317 4.2 13.4 1.0 N B:ALA318 4.3 12.1 1.0 NE2 B:GLN377 4.4 16.3 1.0 CB B:THR317 4.4 14.2 1.0 CA B:ALA318 4.4 11.2 1.0 O B:LEU296 4.5 17.5 1.0 O B:ALA299 4.5 19.0 1.0 O B:ARG297 4.7 20.8 1.0 N B:THR319 4.7 11.4 1.0 O B:HOH2256 4.7 25.4 1.0

D.N.Bolam, S.M.Roberts, M.R.Proctor, J.P.Turkenburg, E.J.Dodson, C.Martinez-Fleites, M.Yang, B.G.Davis, G.J.Davies, H.J.Gilbert. The Crystal Structure of Two Macrolide Glycosyltransferases Provides A Blueprint For Host Cell Antibiotic Immunity. Proc.Nat.Acad.Sci.Usa V. 104 5336 2007.
ISSN: ISSN 0027-8424
PubMed: 17376874
DOI: 10.1073/PNAS.0607897104