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Atomistry » Magnesium » PDB 3i5y-3ig8 » 3iad | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3i5y-3ig8 » 3iad » |
Magnesium in PDB 3iad: Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric ModulatorEnzymatic activity of Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator:
3.1.4.17; Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator, PDB code: 3iad
was solved by
B.L.Staker,
A.B.Burgin Jr.,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3iad:
The structure of Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
(pdb code 3iad). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator, PDB code: 3iad: Jump to Magnesium binding site number: 1; 2; 3; 4; Magnesium binding site 1 out of 4 in 3iadGo back to Magnesium Binding Sites List in 3iad
Magnesium binding site 1 out
of 4 in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
Mono view Stereo pair view
Magnesium binding site 2 out of 4 in 3iadGo back to Magnesium Binding Sites List in 3iad
Magnesium binding site 2 out
of 4 in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
Mono view Stereo pair view
Magnesium binding site 3 out of 4 in 3iadGo back to Magnesium Binding Sites List in 3iad
Magnesium binding site 3 out
of 4 in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
Mono view Stereo pair view
Magnesium binding site 4 out of 4 in 3iadGo back to Magnesium Binding Sites List in 3iad
Magnesium binding site 4 out
of 4 in the Crystal Structure of Human Phosphodiesterase 4D with Bound Allosteric Modulator
Mono view Stereo pair view
Reference:
A.B.Burgin,
O.T.Magnusson,
J.Singh,
P.Witte,
B.L.Staker,
J.M.Bjornsson,
M.Thorsteinsdottir,
S.Hrafnsdottir,
T.Hagen,
A.S.Kiselyov,
L.J.Stewart,
M.E.Gurney.
Design of Phosphodiesterase 4D (PDE4D) Allosteric Modulators For Enhancing Cognition with Improved Safety. Nat.Biotechnol. V. 28 63 2010.
Page generated: Mon Dec 14 08:16:25 2020
ISSN: ISSN 1087-0156 PubMed: 20037581 DOI: 10.1038/NBT.1598 |
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