Magnesium in PDB 3l2c: Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna

The structure of Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna, PDB code: 3l2c was solved by E.Boura, J.Silhan, M.Sulc, J.Brynda, V.Obsilova, T.Obsil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.00 / 1.87
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	40.810, 71.700, 131.860, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 22.8

The binding sites of Magnesium atom in the Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna (pdb code 3l2c). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna, PDB code: 3l2c:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg2 b:21.0 occ:1.00 O C:HOH71 1.9 24.3 1.0 O C:HOH73 2.0 22.2 1.0 O C:HOH74 2.0 16.0 1.0 OP1 C:DT35 2.1 21.4 1.0 O C:HOH70 2.2 21.3 1.0 O C:HOH72 2.2 27.8 1.0 P C:DT35 3.3 24.6 1.0 OP2 C:DT35 3.8 25.2 1.0 O5' C:DT35 4.0 25.5 1.0 O C:HOH75 4.2 24.4 1.0 C5' C:DT35 4.4 26.0 1.0 O3' C:DA34 4.5 22.6 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Dna Binding Domain of FOXO4 Bound to Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1 b:30.0 occ:1.00 O A:LEU154 2.4 16.4 1.0 O A:PHE160 2.6 22.4 1.0 O C:HOH60 2.7 36.2 1.0 O A:HIS157 2.8 23.6 1.0 C A:LEU154 3.6 16.4 1.0 C A:PHE160 3.6 22.3 1.0 O A:SER155 3.6 20.1 1.0 C A:HIS157 3.8 25.5 1.0 O A:HOH230 3.9 51.6 1.0 C A:SER155 3.9 19.7 1.0 CA A:SER155 3.9 18.6 1.0 CZ3 A:TRP174 4.1 11.4 1.0 CB A:PHE160 4.1 20.6 1.0 CA A:PHE160 4.2 22.2 1.0 N A:SER155 4.2 16.6 1.0 N A:PHE160 4.3 24.6 1.0 CA A:SER158 4.4 27.8 1.0 O A:HOH198 4.5 32.4 1.0 N A:SER158 4.5 27.0 1.0 N A:HIS157 4.6 23.9 1.0 C A:SER158 4.7 28.3 1.0 CH2 A:TRP174 4.7 11.7 1.0 N A:ILE161 4.7 21.2 1.0 O A:SER158 4.7 28.4 1.0 CA A:HIS157 4.8 25.2 1.0 N A:LEU156 4.8 22.0 1.0 CA A:LEU154 4.8 14.9 1.0 O A:HOH235 4.8 38.1 1.0

E.Boura, L.Rezabkova, J.Brynda, V.Obsilova, T.Obsil. Structure of the Human FOXO4-Dbd-Dna Complex at 1.9 A Resolution Reveals New Details of Foxo Binding to the Dna Acta Crystallogr.,Sect.D V. 66 1351 2010.
ISSN: ISSN 0907-4449
PubMed: 21123876
DOI: 10.1107/S0907444910042228