Magnesium in PDB 3nky: Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase

The structure of Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase, PDB code: 3nky was solved by R.Agudo, C.Ferrer-Orta, A.Arias, R.Perez-Luque, N.Verdaguer, E.Domingo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.76 / 2.28
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	93.530, 93.530, 121.010, 90.00, 90.00, 90.00
R / Rfree (%)	24 / 26.5

The binding sites of Magnesium atom in the Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase (pdb code 3nky). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase, PDB code: 3nky:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg500 b:60.1 occ:1.00 NH1 A:ARG128 3.4 60.5 1.0 N A:GLU112 3.8 62.0 1.0 NH2 A:ARG128 4.2 60.2 1.0 CG2 A:ILE189 4.2 44.6 1.0 CZ A:ARG128 4.2 61.4 1.0 CA A:MET111 4.3 61.2 1.0 CB A:GLU112 4.4 62.2 1.0 CE A:MET111 4.4 61.4 1.0 CB A:MET111 4.5 62.1 1.0 CG A:MET111 4.5 61.0 1.0 C A:MET111 4.5 62.2 1.0 CA A:GLU112 4.6 63.1 1.0 CG2 A:THR115 4.7 63.2 1.0 CG A:GLU112 4.8 61.5 1.0

Magnesium binding site 2 out of 2 in the Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of A Mutant P44S of Foot-and-Mouth Disease Virus Rna- Dependent Rna Polymerase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:65.0 occ:1.00 O A:HOH513 1.9 66.7 1.0 O A:THR115 2.4 64.6 1.0 C A:THR115 3.4 65.5 1.0 OG1 A:THR115 3.5 62.7 1.0 CB A:ALA116 3.7 66.3 1.0 CA A:THR115 4.2 65.3 1.0 CB A:THR115 4.4 63.5 1.0 N A:ALA116 4.4 66.7 1.0 CA A:ALA116 4.7 67.2 1.0 CG2 A:THR115 5.0 63.2 1.0

R.Agudo, C.Ferrer-Orta, A.Arias, I.De La Higuera, C.Perales, R.Perez-Luque, N.Verdaguer, E.Domingo. A Multi-Step Process of Viral Adaptation to A Mutagenic Nucleoside Analogue By Modulation of Transition Types Leads to Extinction-Escape. Plos Pathog. V. 6 E1001 2010.
ISSN: ISSN 1553-7366
PubMed: 20865120
DOI: 10.1371/JOURNAL.PPAT.1001072