Magnesium in PDB 4a14: Human KIF7, A Kinesin Involved in Hedgehog Signalling

The structure of Human KIF7, A Kinesin Involved in Hedgehog Signalling, PDB code: 4a14 was solved by M.Klejnot, F.Kozielski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.459 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.991, 79.799, 95.094, 90.00, 90.00, 90.00
R / Rfree (%)	18.25 / 20.67

The binding sites of Magnesium atom in the Human KIF7, A Kinesin Involved in Hedgehog Signalling (pdb code 4a14). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human KIF7, A Kinesin Involved in Hedgehog Signalling, PDB code: 4a14:

Magnesium binding site 1 out of 1 in the Human KIF7, A Kinesin Involved in Hedgehog Signalling


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human KIF7, A Kinesin Involved in Hedgehog Signalling within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1346 b:20.0 occ:1.00 O3B A:ADP1345 2.0 17.9 1.0 OG1 A:THR98 2.1 21.8 1.0 O A:HOH2127 2.1 19.9 1.0 O A:HOH2126 2.1 20.8 1.0 O A:HOH2128 2.1 21.6 1.0 O A:HOH2324 2.2 22.4 1.0 CB A:THR98 3.1 22.6 1.0 PB A:ADP1345 3.3 18.6 1.0 O2B A:ADP1345 3.5 23.0 1.0 N A:THR98 3.9 18.1 1.0 O A:HOH2238 4.0 24.2 1.0 CA A:THR98 4.1 22.2 1.0 O A:HOH2070 4.1 42.8 1.0 O2A A:ADP1345 4.1 22.6 1.0 CG2 A:THR98 4.1 22.9 1.0 OD2 A:ASP249 4.2 20.9 1.0 O3A A:ADP1345 4.3 20.4 1.0 OD1 A:ASP249 4.3 20.0 1.0 O A:HOH2071 4.3 39.7 1.0 O1B A:ADP1345 4.3 20.0 1.0 O A:HOH2241 4.4 20.6 1.0 PA A:ADP1345 4.5 21.1 1.0 O A:HOH2123 4.6 20.6 1.0 CG A:ASP249 4.7 26.2 1.0 O1A A:ADP1345 4.8 23.2 1.0 CE A:LYS97 4.9 18.9 1.0 O A:HOH2072 4.9 41.3 1.0 O A:HOH2124 4.9 27.8 1.0 CB A:LYS97 5.0 18.1 1.0 C A:LYS97 5.0 16.0 1.0

M.Klejnot, F.Kozielski. Structural Insights Into Human KIF7, A Kinesin Involved in Hedgehog Signalling. Acta Crystallogr.,Sect.D V. 68 154 2012.
ISSN: ISSN 0907-4449
PubMed: 22281744
DOI: 10.1107/S0907444911053042