Magnesium in PDB 4c06: Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2

All present enzymatic activity of Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2:
2.1.1.125;

The structure of Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2, PDB code: 4c06 was solved by L.Bonnefond, V.Cura, N.Troffer-Charlier, J.Mailliot, J.M.Wurtz, J.Cavarelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.923 / 1.60
Space group	I 41
Cell size a, b, c (Å), α, β, γ (°)	79.758, 79.758, 118.945, 90.00, 90.00, 90.00
R / Rfree (%)	15.54 / 19.39

The binding sites of Magnesium atom in the Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2 (pdb code 4c06). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2, PDB code: 4c06:

Magnesium binding site 1 out of 1 in the Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 with MGCL2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1378 b:21.8 occ:0.61 O A:HOH2355 2.0 32.0 1.0 O A:HOH2023 2.0 31.7 1.0 O A:HOH2024 2.1 41.1 1.0 O A:HOH2354 2.1 34.1 1.0 O A:HOH2139 2.1 30.5 1.0 O A:HOH2143 2.1 34.8 1.0 HE2 A:HIS320 3.4 26.3 1.0 O A:HOH2140 3.7 43.1 1.0 O A:HOH2069 3.9 48.0 1.0 OE2 A:GLU158 4.0 29.9 1.0 O A:MET160 4.0 14.7 1.0 O A:HOH2138 4.0 32.3 1.0 SD A:MET63 4.1 54.7 1.0 HG2 A:MET63 4.1 51.5 1.0 OE1 A:GLU158 4.2 26.8 1.0 O A:HOH2141 4.2 41.7 1.0 NE2 A:HIS320 4.3 21.9 1.0 HE1 A:TRP321 4.4 21.5 1.0 CD A:GLU158 4.5 28.1 1.0 CG A:MET63 4.5 42.9 1.0 HG3 A:MET63 4.7 51.5 1.0 HZ2 A:TRP321 4.7 19.8 1.0 HE1 A:MET63 4.7 22.4 1.0 HA2 A:GLY161 4.8 18.2 1.0 O A:HOH2013 4.9 42.5 1.0 NE1 A:TRP321 5.0 17.9 1.0 CE A:MET63 5.0 18.7 1.0

L.Bonnefond, V.Cura, N.Troffer-Charlier, J.Mailliot, J.M.Wurtz, J.Cavarelli. Crystal Structure of M. Musculus Protein Arginine Methyltransferase PRMT6 To Be Published.